PPP1R37 and RBMY1J

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPP1R37	RBMY1J
Description		protein phosphatase 1 regulatory subunit 37	RNA binding motif protein Y-linked family 1 member J
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Nucleolus
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process		MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 23565137) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064) Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		12 interacting genes: BEND7 FOXH1 HNRNPCL2 KRTAP6-3 PATZ1 PPP1CA RBMY1F RBMY1J RBPMS2 ZMYND19 ZNF764 ZNF837	28 interacting genes: APOBEC3C CBX2 CNNM3 EPM2AIP1 HHEX HNRNPK LNX1 NPDC1 PCDHB14 PPP1R37 PRPF31 PRR3 RASD1 RBM3 RBMX RBMY1A1 RBMY1E RBMY1F RNPS1 SNRPA SPATC1L TRA2B U2AF2 YTHDC1 ZNF317 ZNF408 ZNF792 ZNF837
Entrez ID		284352	378951
HPRD ID			15233
Ensembl ID		ENSG00000104866	ENSG00000226941
Uniprot IDs		O75864	Q15415
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of MRNA Metabolic Process	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Spliceosomal Complex Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing MRNA Processing Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nucleic Acid Binding RNA Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleus Regulation Of Gene Expression MRNA Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Ribonucleoprotein Complex Localization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cytoplasmic Translational Initiation Ribonucleoprotein Complex Poly-pyrimidine Tract Binding U4atac SnRNP
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