PPP1R37 and ZNF837

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPP1R37	ZNF837
Description		protein phosphatase 1 regulatory subunit 37	zinc finger protein 837
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 23565137) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064) Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		12 interacting genes: BEND7 FOXH1 HNRNPCL2 KRTAP6-3 PATZ1 PPP1CA RBMY1F RBMY1J RBPMS2 ZMYND19 ZNF764 ZNF837	77 interacting genes: BAHD1 CARD10 CATSPER1 CCDC125 CCDC136 CCNDBP1 CDC37 CHIC2 CLK2 CYSRT1 DHX57 DVL3 EFEMP2 EHMT2 FSD2 GOLGA6L9 GPATCH2L HOXA1 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-5 KRTAP5-9 MDFI MTUS2 MYO15B NBPF19 NOTCH2NLA PCSK5 PHF19 PPARD PPP1R37 PRPF31 RBMY1F RBMY1J RSPO2 SPRED2 SPRY1 TCEANC TNS2 TRIM41 TRMT2A UBE2I VWC2 ZBTB24 ZBTB48 ZBTB8A ZNF121 ZNF124 ZNF165 ZNF17 ZNF202 ZNF250 ZNF275 ZNF330 ZNF408 ZNF417 ZNF473 ZNF497 ZNF524 ZNF526 ZNF552 ZNF587 ZNF639 ZNF648 ZNF655 ZNF764 ZNF792 ZNF835 ZRANB1 ZSCAN21
Entrez ID		284352	116412
HPRD ID
Ensembl ID		ENSG00000104866	ENSG00000152475
Uniprot IDs		O75864	Q96EG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of MRNA Metabolic Process	Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Keratin Filament Intermediate Filament Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Hair Cycle Nucleus Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Macromolecule Metabolic Process Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding
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