PPP1R37 and RBMY1F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPP1R37	RBMY1F
Description		protein phosphatase 1 regulatory subunit 37	RNA binding motif protein Y-linked family 1 member F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Nucleolus
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process		MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 23565137) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064) Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		12 interacting genes: BEND7 FOXH1 HNRNPCL2 KRTAP6-3 PATZ1 PPP1CA RBMY1F RBMY1J RBPMS2 ZMYND19 ZNF764 ZNF837	35 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 CNNM3 DAAM2 EPM2AIP1 HHEX HNRNPK LNX1 NPDC1 PCDHB14 PPP1R37 PRPF31 PRR3 RAMAC RASD1 RBM10 RBM3 RBMX RBMY1A1 RBMY1E RBMY1J RNPS1 SNRPA SPATC1L TRA2B U2AF2 YTHDC1 ZNF317 ZNF385C ZNF408 ZNF792 ZNF837
Entrez ID		284352	159163
HPRD ID			15232
Ensembl ID		ENSG00000104866	ENSG00000169800
Uniprot IDs		O75864	J3KQ82 Q15415
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of MRNA Metabolic Process	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing Positive Regulation Of RNA Splicing Spliceosomal Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process MRNA Processing Nucleic Acid Binding RNA Splicing RNA Processing MRNA Metabolic Process RNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Nucleus Nucleic Acid Metabolic Process Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Binding Nuclear Speck Protein Binding Negative Regulation Of Gene Expression Regulation Of Metabolic Process Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Biosynthetic Process Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Ribonucleoprotein Complex Localization U4/U6 X U5 Tri-snRNP Complex
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