ZNF837 and TRMT2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF837	TRMT2A
Description		zinc finger protein 837	tRNA methyltransferase 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding Methyltransferase Activity C-methyltransferase Activity RNA Methyltransferase Activity Transferase Activity TRNA (uracil(54)-C5)-methyltransferase Activity, S-adenosyl Methionine-dependent
	Biological Process	Regulation Of Transcription By RNA Polymerase II	RNA Processing MRNA Processing TRNA Processing Methylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		77 interacting genes: BAHD1 CARD10 CATSPER1 CCDC125 CCDC136 CCNDBP1 CDC37 CHIC2 CLK2 CYSRT1 DHX57 DVL3 EFEMP2 EHMT2 FSD2 GOLGA6L9 GPATCH2L HOXA1 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-5 KRTAP5-9 MDFI MTUS2 MYO15B NBPF19 NOTCH2NLA PCSK5 PHF19 PPARD PPP1R37 PRPF31 RBMY1F RBMY1J RSPO2 SPRED2 SPRY1 TCEANC TNS2 TRIM41 TRMT2A UBE2I VWC2 ZBTB24 ZBTB48 ZBTB8A ZNF121 ZNF124 ZNF165 ZNF17 ZNF202 ZNF250 ZNF275 ZNF330 ZNF408 ZNF417 ZNF473 ZNF497 ZNF524 ZNF526 ZNF552 ZNF587 ZNF639 ZNF648 ZNF655 ZNF764 ZNF792 ZNF835 ZRANB1 ZSCAN21	22 interacting genes: AIMP2 ANXA7 APP APPBP2 ATP1B1 CDK4 CDKN1A GADD45G MCC MEOX2 MESD PICK1 PIK3R3 PIN1 RASA1 RCC1 SMN1 TK1 TLE5 TNFSF11 UBC ZNF837
Entrez ID		116412	27037
HPRD ID			13719
Ensembl ID		ENSG00000152475	ENSG00000099899
Uniprot IDs		Q96EG3	F2Z2W7 Q8IZ69
PDB IDs			7NTN 7NTO
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Keratin Filament Intermediate Filament Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Hair Cycle Nucleus Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Macromolecule Metabolic Process Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding	Regulation Of Wnt Signaling Pathway Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Regulation Of Anoikis Positive Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Response To Phorbol 13-acetate 12-myristate Cytoplasm Low-density Lipoprotein Particle Receptor Binding Intracellular Signaling Cassette Positive Regulation Of JNK Cascade Molecular Function Activator Activity Protein Serine/threonine Kinase Binding Regulation Of Mitotic Cell Cycle Positive Regulation Of Receptor Internalization Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle
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