TSEN54 and MRPL38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSEN54	MRPL38
Description		tRNA splicing endonuclease subunit 54	mitochondrial ribosomal protein L38
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GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Nucleolus	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Cytosol Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing TRNA Processing	Mitochondrial Translation
Pathways		tRNA processing in the nucleus	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases		Pontocerebellar hypoplasia
GWAS		Deep white matter hyperintensities ( 32517579) FEV1 ( 30804560) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Platelet count ( 32888494) Plateletcrit ( 32888494) Sight-threatening diabetic retinopathy in type 2 diabetes ( 26188370)	White matter hyperintensities ( 30002152)
Interacting Genes		20 interacting genes: BRCA1 CCDC57 CSNK2B GOLGA6L9 IRF4 KPNA5 KRT31 LHX3 LHX4 LMO2 MCPH1 MRPL38 NAA10 NCKIPSD NFKBID RINT1 TRIM23 TRIML2 TSEN2 ZMYND12	21 interacting genes: ARHGAP9 BAG3 BEX2 BTG3 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GOLGA6A HSPB3 LONRF1 MKRN3 MYOZ3 PPP1R18 PRIM1 RALY TSEN54 UBC
Entrez ID		283989	64978
HPRD ID		12291	14758
Ensembl ID		ENSG00000182173	ENSG00000204316
Uniprot IDs		Q7Z6J9	Q96DV4
PDB IDs		7UXA 7ZRZ 8HMY 8HMZ 8ISS	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Medial Motor Column Neuron Differentiation	Positive Regulation Of Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining
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