NHLRC4 and CERK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NHLRC4	CERK
Description		NHL repeat containing 4	ceramide kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Magnesium Ion Binding Ceramide Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity
	Biological Process		Lipid Metabolic Process Ceramide Metabolic Process Glycosphingolipid Biosynthetic Process
Pathways			Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 27863252)	Aseptic loosening in total joint arthroplasty ( 31791832) Triglyceride levels ( 30108155)
Interacting Genes		20 interacting genes: CERK DDIT4L DMRT3 DTX2 ENKD1 HSF4 IGFN1 KRTAP13-2 KRTAP15-1 KRTAP26-1 MGAT5B MYLIP OTX1 PATZ1 PITX1 POGZ POU4F3 PRKAB2 SPAG8 TLX3	21 interacting genes: ALAS1 APP CRYBA1 CYSRT1 KRT34 KRTAP1-1 KRTAP10-3 KRTAP11-1 KRTAP19-1 KRTAP19-6 KRTAP3-1 KRTAP3-2 KRTAP6-2 KRTAP9-2 MTUS2 NBPF19 NHLRC4 NOTCH2NLA OIP5 PLEKHF2 TRIM42
Entrez ID		283948	64781
HPRD ID		11681	09878
Ensembl ID		ENSG00000257108	ENSG00000100422
Uniprot IDs		P0CG21	Q8TCT0
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequence-specific Double-stranded DNA Binding Chromatin DNA-binding Transcription Factor Activity Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Diencephalon Morphogenesis Neuron Fate Specification Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Intermediate Filament	Intermediate Filament Keratin Filament Structural Molecule Activity
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