IFNL1 and IFNLR1

Number of citations of the paper that reports this interaction (PMID 12469119)
211

Data Source:
HPRD (in vivo)

		IFNL1	IFNLR1
Gene Name		interferon, lambda 1	interferon, lambda receptor 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Interleukin-28 Receptor Complex	Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Receptor Binding Cytokine Activity Interleukin-28 Receptor Binding	Cytokine Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Type 2 Immune Response JAK-STAT Cascade Negative Regulation Of Cell Proliferation Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Memory T Cell Differentiation Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JAK-STAT Cascade Positive Regulation Of Immune Response Defense Response To Virus	Mucosal Immune Response Negative Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Response To Type III Interferon Regulation Of Defense Response To Virus By Host Defense Response To Virus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: IFNLR1	3 interactors: IFNL1 IFNL2 LSM8
Entrez ID		282618	163702
HPRD ID		09588	09589
Ensembl ID		ENSG00000182393	ENSG00000185436
Uniprot IDs		Q8IU54	Q8IU57
PDB IDs		3OG4 3OG6	3OG4 3OG6
Enriched GO Terms of Interacting Partners?		Response To Type III Interferon Regulation Of Defense Response To Virus By Host Mucosal Immune Response Regulation Of Defense Response To Virus Defense Response To Virus	JAK-STAT Cascade Negative Regulation Of Memory T Cell Differentiation Defense Response To Virus Response To Virus Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Regulation Of Memory T Cell Differentiation Positive Regulation Of Immune Response Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Type 2 Immune Response Response To Other Organism Response To Biotic Stimulus Regulation Of Interleukin-5 Production Regulation Of Immune Response Mucosal Immune Response Positive Regulation Of Immune System Process Negative Regulation Of T Cell Differentiation Regulation Of Type 2 Immune Response Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Lymphocyte Differentiation Positive Regulation Of Interferon-gamma Production Positive Regulation Of JAK-STAT Cascade Regulation Of Immune System Process Defense Response
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?