GNRHR and GNRH1

Number of citations of the paper that reports this interaction (PMID 9414473)
2

Data Source:
HPRD (in vivo)

		GNRHR	GNRH1
Gene Name		gonadotropin-releasing hormone receptor	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	Gonadotropin-releasing Hormone Receptor Activity Peptide Binding	Hormone Activity Gonadotropin Hormone-releasing Hormone Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Cellular Response To Gonadotropin-releasing Hormone	Signal Transduction Cell-cell Signaling Multicellular Organismal Development Female Pregnancy Negative Regulation Of Cell Proliferation Regulation Of Gene Expression Response To Corticosteroid Ovulation Cycle Negative Regulation Of Apoptotic Process Response To Ethanol Regulation Of Ovarian Follicle Development Negative Regulation Of Neuron Migration
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding	G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Degarelix Buserelin
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GNRH1 RGS10	2 interactors: GNRHR MEP1A
Entrez ID		2798	2796
HPRD ID		00732	08860
Ensembl ID			ENSG00000147437
Uniprot IDs		P30968	P01148
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ovarian Follicle Development Regulation Of Female Gonad Development	Cellular Response To Gonadotropin-releasing Hormone
Tagcloud ?		aas aass abused anabolic androgenic arr19 cyp11a1 cyp17a1 dax1 disturbed enanthate hsd17b4 hsd3b1 hsd3b5 insl3 intramuscular leydig lhcgr milieu oppositely prka prlr1 prlr2 prolactin star steroidogenesis steroidogenic testosterone tspo	12h absolutely acting breeding counter darkness daylight exceed gradually happens latitudes naturally net photo photoperiod photoperiods photorefractory prevailing progresses proposes protocols reverses reviews seasons secretion sometimes tandem timing
Tagcloud (Difference) ?		aas aass abused anabolic androgenic arr19 cyp11a1 cyp17a1 dax1 disturbed enanthate hsd17b4 hsd3b1 hsd3b5 insl3 intramuscular leydig lhcgr milieu oppositely prka prlr1 prlr2 prolactin star steroidogenesis steroidogenic testosterone tspo	12h absolutely acting breeding counter darkness daylight exceed gradually happens latitudes naturally net photo photoperiod photoperiods photorefractory prevailing progresses proposes protocols reverses reviews seasons secretion sometimes tandem timing
Tagcloud (Intersection) ?