TMEM121B and HMGN1

		TMEM121B	HMGN1
Description		transmembrane protein 121B	high mobility group nucleosome binding domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Female Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm
	Molecular Function		DNA Binding Chromatin Binding Protein Binding Nucleosomal DNA Binding
	Biological Process		Pyrimidine Dimer Repair By Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair Chromatin Organization Regulation Of Transcription By RNA Polymerase II Response To UV-B Response To UV-C Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Development, Heterochronic Post-embryonic Camera-type Eye Morphogenesis Regulation Of Epithelial Cell Proliferation
Pathways
Drugs
Diseases
GWAS			LDL cholesterol levels ( 32203549) Lipoprotein (a) levels ( 33730874) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes			22 interacting genes: CDC42 CEBPA CHEK2 EP300 GSK3A HMGN2 HPF1 IRF2 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 YWHAZ
Entrez ID		27439	3150
HPRD ID		16704	01231
Ensembl ID		ENSG00000183307	ENSG00000205581
Uniprot IDs		Q9BXQ6	P05114 Q6NSG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Pyrimidine Dimer Repair Regulation Of Development, Heterochronic Pyrimidine Dimer Repair By Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair Female Germ Cell Nucleus Post-embryonic Camera-type Eye Morphogenesis Response To UV-C Post-embryonic Eye Morphogenesis Response To UV-B Nucleosomal DNA Binding Nucleotide-excision Repair Positive Regulation Of DNA-templated Transcription, Elongation Eye Morphogenesis Sensory Organ Morphogenesis Regulation Of DNA-templated Transcription Elongation Response To UV	TORC1 Signaling Regulation Of Nucleobase-containing Compound Metabolic Process TOR Signaling Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Intracellular Signal Transduction Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Response To Stress Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Component Organization Regulation Of Macromolecule Metabolic Process Response To Nutrient Levels Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Response To Steroid Hormone Protein Serine Kinase Activity Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Differentiation Protein Domain Specific Binding Cellular Response To Stress Regulation Of DNA-templated Transcription Response To Gamma Radiation Regulation Of RNA Biosynthetic Process Cellular Response To Lithium Ion Regulation Of Gene Expression Protein Serine/threonine Kinase Activity Regulation Of Metabolic Process Response To Lithium Ion Chromatin Organization Histone H3S28 Kinase Activity Response To Hormone Regulation Of Transcription By RNA Polymerase II Protein Kinase Binding Chromatin Remodeling Negative Regulation Of Macromolecule Metabolic Process Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Cellular Response To Radiation Chromosome, Telomeric Region Nucleus Negative Regulation Of Biosynthetic Process Protein Kinase Activity Protein Modification Process Protein Phosphorylation
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