GOLIM4 and NUP54

		GOLIM4	NUP54
Description		golgi integral membrane protein 4	nucleoporin 54
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen Cis-Golgi Network Endosome Membrane Membrane Transport Vesicle Endocytic Vesicle Golgi Cisterna Membrane	Nucleus Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Nuclear Pore Central Transport Channel
	Molecular Function		Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process		NLS-bearing Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Protein Transport Protein Localization To Nuclear Inner Membrane MRNA Transport
Pathways		Intra-Golgi traffic	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Dimensional psychopathology (Arousal) ( 29496196) Epilepsy ( 25087078) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 18391951) Response to metformin (IC50) ( 28173075) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Age at first birth ( 34211149) Hippocampal volume ( 29274321)
Interacting Genes		2 interacting genes: GOLPH3 GOLPH3L	46 interacting genes: AGR2 AIRIM AP1B1 AP2B1 APC BPIFA1 C14orf119 C21orf91 CCDC85B CCHCR1 CDC23 CENPH DCTN3 DGCR6 EFHC1 EIF3F EXOC1 EXOC8 HAUS1 HAUS8 HGS IFT20 KPNA1 KPNB1 KRT15 KRT27 KRT33B NFKBID NR3C1 NUP62 NUTF2 OGT OIP5 PKNOX2 SMYD3 SOHLH1 SPG21 SSR1 TACC3 TCHP TEKT1 TEX12 TPM3 TRIM54 VPS37C ZWINT
Entrez ID		27333	53371
HPRD ID		08429	06352
Ensembl ID		ENSG00000173905	ENSG00000138750
Uniprot IDs		F8W785 O00461	A0A8Q3SHX2 A0A8Q3WLP2 Q7Z3B4
PDB IDs			4JNU 4JNV 4JO7 4JO9 5IJN 5IJO 7N8R 7PER 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Protein Localization To Membrane Establishment Of Protein Localization To Organelle Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Localization Within Membrane Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Protein Transport Trans-Golgi Network Asymmetric Golgi Ribbon Formation Protein Localization To Plasma Membrane Establishment Of Protein Localization Protein Targeting Establishment Of Protein Localization To Membrane Protein Localization To Nuclear Inner Membrane Protein Localization To Cell Periphery Cell Adhesion Molecule Production Cellular Response To Rapamycin Positive Regulation Of Protein Transport Cellular Localization Regulation Of Protein Secretion Protein Retention In Golgi Apparatus Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Nuclear Pore Central Transport Channel Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Response To Rapamycin Intracellular Protein Localization Lipid Binding Golgi Ribbon Formation Regulation Of Protein Transport Positive Regulation Of Protein Localization Cellular Response To Ether Protein Localization To Nuclear Envelope Nuclear Pore Organization Regulation Of Establishment Of Protein Localization Organelle Organization	Cytoskeleton Cytoskeleton-dependent Cytokinesis Centrosome Organelle Assembly Cell Division Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Establishment Of Protein Localization Membrane Fission Microtubule-based Process Intracellular Protein Transport Nuclear Import Signal Receptor Activity Organelle Organization Protein Transport Mitotic Cytokinesis Cytosol Spindle Cellular Localization Chromosome Localization Spindle Pole Regulation Of Microtubule-based Process Nuclear Pore Protein Binding Nuclear Pore Central Transport Channel Membraneless Organelle Assembly Keratin Filament Mitotic Spindle Organization Positive Regulation Of Protein Localization To Centrosome Metaphase/anaphase Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Hsp90 Protein Binding Metaphase/anaphase Transition Of Cell Cycle HAUS Complex Regulation Of Sister Chromatid Segregation Vesicle Tethering Involved In Exocytosis Intracellular Protein Localization Mitotic Metaphase Chromosome Alignment Organelle Localization NLS-dependent Protein Nuclear Import Complex Centrosome Cycle Regulation Of Mitotic Nuclear Division Protein Import Into Nucleus Establishment Of Protein Localization To Organelle Intracellular Transport Protein Localization To Organelle Import Into Nucleus Clathrin Adaptor Complex Regulation Of Protein Localization To Centrosome Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Chromosome Segregation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?