GOLIM4 and GOLPH3

Number of citations of the paper that reports this interaction (PubMedID 34473204)
68

Data Source:
BioGRID (pull down)

		GOLIM4	GOLPH3
Description		golgi integral membrane protein 4	golgi phosphoprotein 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen Cis-Golgi Network Endosome Membrane Membrane Transport Vesicle Endocytic Vesicle Golgi Cisterna Membrane	Golgi Membrane Mitochondrion Mitochondrial Intermembrane Space Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Membrane Golgi Cisterna Golgi Cisterna Membrane
	Molecular Function		Protein Binding Lipid Binding Enzyme Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity
	Biological Process		Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Glycoprotein Biosynthetic Process Protein Secretion Gene Expression Regulation Of Mitochondrion Organization Protein Transport Cell Migration Lamellipodium Assembly Positive Regulation Of TOR Signaling Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Protein Retention In Golgi Apparatus Golgi Vesicle Budding Positive Regulation Of Protein Secretion Leukocyte Tethering Or Rolling Cell Adhesion Molecule Production Cellular Response To Rapamycin Golgi Ribbon Formation Asymmetric Golgi Ribbon Formation Protein Targeting To Golgi Apparatus
Pathways		Intra-Golgi traffic
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Dimensional psychopathology (Arousal) ( 29496196) Epilepsy ( 25087078) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 18391951) Response to metformin (IC50) ( 28173075) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: GOLPH3 GOLPH3L	23 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2
Entrez ID		27333	64083
HPRD ID		08429	11007
Ensembl ID		ENSG00000173905	ENSG00000113384
Uniprot IDs		F8W785 O00461	Q9H4A6
PDB IDs			3KN1
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Protein Localization To Membrane Establishment Of Protein Localization To Organelle Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Localization Within Membrane Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Protein Transport Trans-Golgi Network Asymmetric Golgi Ribbon Formation Protein Localization To Plasma Membrane Establishment Of Protein Localization Protein Targeting Establishment Of Protein Localization To Membrane Protein Localization To Nuclear Inner Membrane Protein Localization To Cell Periphery Cell Adhesion Molecule Production Cellular Response To Rapamycin Positive Regulation Of Protein Transport Cellular Localization Regulation Of Protein Secretion Protein Retention In Golgi Apparatus Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Nuclear Pore Central Transport Channel Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Response To Rapamycin Intracellular Protein Localization Lipid Binding Golgi Ribbon Formation Regulation Of Protein Transport Positive Regulation Of Protein Localization Cellular Response To Ether Protein Localization To Nuclear Envelope Nuclear Pore Organization Regulation Of Establishment Of Protein Localization Organelle Organization	Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Carbohydrate Derivative Metabolic Process Glycosylation Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine Transferase Activity Macromolecule Biosynthetic Process Protein Modification Process Protein Metabolic Process Membrane Polypeptide N-acetylgalactosaminyltransferase Activity Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane Carbohydrate Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Golgi Stack Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Trans-Golgi Network Protein Homodimerization Activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Leukocyte Cell-cell Adhesion
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