TNRC6A and TXNL4A

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		TNRC6A	TXNL4A
Description		trinucleotide repeat containing adaptor 6A	thioredoxin like 4A
Image
GO Annotations	Cellular Component	P-body Nucleoplasm Cytoplasm Golgi Apparatus Cytosol RISC Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Protein-macromolecule Adaptor Activity	Protein Binding
	Biological Process	Regulation Of Translation Endoderm Development Cellular Response To Starvation Regulatory NcRNA-mediated Gene Silencing P-body Assembly MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Division
Pathways		Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Post-transcriptional silencing by small RNAs Transcriptional regulation by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH1 mRNA translation by microRNAs Regulation of NPAS4 mRNA translation Regulation of MITF-M-dependent genes involved in apoptosis TGFBR3 expression Regulation of PD-L1(CD274) translation	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30679032 30643258) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Metabolic syndrome ( 31589552) Problematic alcohol use ( 32451486) Pulse pressure ( 30578418 27618448 27841878) Smoking initiation ( 33082346) Systolic blood pressure ( 27841878 27618448 30578418) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: DMRTB1 PAN2 QKI RBFOX2 SMARCB1 TRIM65 TRIP13 TXNL4A UBC WNK1	20 interacting genes: ALG13 ANKHD1 CD2BP2 CPSF7 DDIT4L DMRTB1 ERBB3 EXOC5 HNRNPF KRT31 LARP4 LZTS2 PQBP1 PRRC2B QKI RBM22 RBPMS RHEBL1 SNW1 TNRC6A
Entrez ID		27327	10907
HPRD ID		11640	18252
Ensembl ID		ENSG00000090905	ENSG00000141759
Uniprot IDs		Q8NDV7	K7ESL1 P83876
PDB IDs		5W6V 7RUP	1PQN 1QGV 1SYX 3JCR 4BWQ 4BWS 4CDO 5O9Z 6AH0 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Macromolecule Metabolic Process MRNA Processing	Regulation Of RNA Splicing Nucleic Acid Binding MRNA Processing MRNA Splicing, Via Spliceosome RNA Binding RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Splicing Cytoplasmic Stress Granule Catalytic Step 2 Spliceosome Pre-mRNA Binding Transcription Coactivator Activity Regulation Of MRNA Splicing, Via Spliceosome MRNA 3'-UTR Binding Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing U2-type Catalytic Step 2 Spliceosome Positive Regulation Of MRNA Metabolic Process RNA Metabolic Process Ribonucleoprotein Complex Binding Spliceosomal Complex Internal N(7)-methylguanine-containing RNA Reader Activity Positive Regulation Of RNA Splicing N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Primary Ureteric Bud Growth
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?