TNFRSF21 and STX11

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TNFRSF21	STX11
Gene Name		tumor necrosis factor receptor superfamily, member 21	syntaxin 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Axon Intrinsic Component Of Plasma Membrane	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	B Cell Apoptotic Process Adaptive Immune Response Apoptotic Process Humoral Immune Response Negative Regulation Of B Cell Proliferation Negative Regulation Of Myelination Negative Regulation Of T Cell Proliferation Myelination Cellular Lipid Metabolic Process Small Molecule Metabolic Process Regulation Of Oligodendrocyte Differentiation T Cell Receptor Signaling Pathway Neuron Apoptotic Process Cellular Response To Tumor Necrosis Factor Oligodendrocyte Apoptotic Process Negative Regulation Of Interleukin-5 Secretion Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-10 Secretion	Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Membrane Neutrophil Degranulation Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Vesicle Docking Membrane Fusion
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Panic disorder ( 19165232)
Protein-Protein Interactions		6 interactors: CLIP3 MATR3 NSD1 STX11 TRADD WASH2P	62 interactors: AES APP BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 FHL5 GOLGA8EP GOLGA8F HAUS1 IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 STXBP1 SUV39H1 TAF6L TBK1 TCF4 TNFRSF21 USHBP1 VAMP2 VPS52 WDYHV1 ZCCHC10 ZNF417 ZNF587
Entrez ID		27242	8676
HPRD ID		05759	09231
Ensembl ID		ENSG00000146072
Uniprot IDs		O75509	O75558
PDB IDs		2DBH 3QO4 3U3P 3U3Q 3U3S 3U3T 3U3V
Enriched GO Terms of Interacting Partners?		Peptidyl-L-cysteine S-palmitoylation Neutrophil Degranulation Cytotoxic T Cell Degranulation Chaperone-mediated Protein Transport Neutrophil Activation Involved In Immune Response Regulation Of Protein Complex Assembly Histone H3-K36 Methylation Natural Killer Cell Degranulation Positive Regulation Of Hair Follicle Development Synaptic Vesicle Fusion To Presynaptic Membrane T Cell Mediated Cytotoxicity Negative Regulation Of Microtubule Polymerization Histone H4-K20 Methylation Regulation Of Hair Follicle Development Regulation Of Cytoskeleton Organization Neutrophil Mediated Immunity Neutrophil Activation Regulation Of Hair Cycle Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Natural Killer Cell Activation Involved In Immune Response Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Protein Localization To Plasma Membrane Natural Killer Cell Mediated Immunity Membrane Biogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Microtubule Polymerization Protein Palmitoylation Positive Regulation Of Cell Death Positive Regulation Of Epidermis Development T Cell Mediated Immunity Leukocyte Mediated Cytotoxicity	Neurotransmitter Secretion Glutamate Secretion Vesicle Localization Regulation Of Neurotransmitter Levels Neurotransmitter Transport Gene Expression Organelle Localization Synaptic Vesicle Transport Establishment Of Vesicle Localization Establishment Of Organelle Localization Vesicle Organization Synaptic Vesicle Exocytosis Acid Secretion Energy Reserve Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Dicarboxylic Acid Transport Organelle Organization Membrane Docking Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Exocytosis RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Secretion By Cell Regulation Of RNA Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of RNA Metabolic Process Viral Process Synaptic Vesicle Docking Membrane Fusion Axon Cargo Transport Synaptic Vesicle Priming Regulation Of Nitrogen Compound Metabolic Process Establishment Of Localization In Cell Vesicle Fusion Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Generation Of Precursor Metabolites And Energy Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Macromolecule Biosynthetic Process Cellular Localization
Tagcloud ?		87mg ags alteration arrayed bad bcl2 bcl2l11 bfar bnip3l casp7 cidea cideb combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tp73 traf3 uncovering	autosomal characterised defect done dysregulation familial families fhl haemophagocytic harbour harbouring killer leukaemia lymphohistiocytosis milder mutational myelogenous nonsense perforin periods prf1 psychomotor recessive retardation segregation syntaxin uncommon undertaken unrelated
Tagcloud (Difference) ?		87mg ags alteration arrayed bad bcl2 bcl2l11 bfar bnip3l casp7 cidea cideb combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tp73 traf3 uncovering	autosomal characterised defect done dysregulation familial families fhl haemophagocytic harbour harbouring killer leukaemia lymphohistiocytosis milder mutational myelogenous nonsense perforin periods prf1 psychomotor recessive retardation segregation syntaxin uncommon undertaken unrelated
Tagcloud (Intersection) ?