TNFRSF21

Description		TNF receptor superfamily member 21
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding
	Biological Process	B Cell Apoptotic Process Adaptive Immune Response Immune System Process Apoptotic Process Humoral Immune Response Signal Transduction Axonal Fasciculation Negative Regulation Of B Cell Proliferation Negative Regulation Of Myelination Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Negative Regulation Of T Cell Proliferation Myelination Regulation Of Oligodendrocyte Differentiation T Cell Receptor Signaling Pathway Neuron Apoptotic Process Cellular Response To Tumor Necrosis Factor Oligodendrocyte Apoptotic Process
Pathways		PPARA activates gene expression
Drugs
Diseases
GWAS		Panic disorder ( 19165232) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
Novel Interacting Genes		1 novel interacting genes: PTK7
Interacting Genes		8 interacting genes: CLIP3 MATR3 MMP14 NSD1 SGTA STX11 TRADD WASH2P
Entrez ID		27242
HPRD ID		05759
Ensembl ID		ENSG00000146072
Uniprot IDs		O75509
PDB IDs		2DBH 3QO4 3U3P 3U3Q 3U3S 3U3T 3U3V
Enriched GO Terms of Interacting Partners?		Cellular Response To Genistein Negative Regulation Of GDF15-GFRAL Signaling Pathway Cardiac Septum Development Ventricular Septum Development Ganglioside Binding
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