IL17B and ENO2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IL17B	ENO2
Gene Name		interleukin 17B	enolase 2 (gamma, neuronal)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytosol Plasma Membrane Perikaryon Extracellular Vesicular Exosome
	Molecular Function	Cytokine Activity	Magnesium Ion Binding Phosphopyruvate Hydratase Activity
	Biological Process	Inflammatory Response Immune Response Cell-cell Signaling Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Small Molecule Metabolic Process
Pathways			Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ENO2 IL17RB UBC	23 interactors: A2M ACD ANXA11 C16orf45 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C
Entrez ID		27190	2026
HPRD ID		05217	00573
Ensembl ID		ENSG00000127743	ENSG00000111674
Uniprot IDs		Q9UHF5	P09104 Q6FHV6
PDB IDs			1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS
Enriched GO Terms of Interacting Partners?		Glucose Metabolic Process Carbohydrate Biosynthetic Process Pathogenesis Hexose Metabolic Process Monosaccharide Metabolic Process Generation Of Precursor Metabolites And Energy Cytokine-mediated Signaling Pathway Viral Protein Processing Cellular Response To Cytokine Stimulus Response To Cytokine Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Carbohydrate Metabolic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Gluconeogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Hexose Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Mitotic Cell Cycle Process Organelle Organization Cell Division Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Platelet Degranulation Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Regulation Of Organelle Organization Cell Cycle Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly G2/M Transition Of Mitotic Cell Cycle RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Exocytosis Cell Cycle Process Positive Regulation Of DNA Metabolic Process Protein Localization To Chromosome Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Negative Regulation Of Catalytic Activity Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Platelet Activation Cellular Localization Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Protein ADP-ribosylation
Tagcloud ?		17beta chondrocyte chondrocytes connective ctgf cxcl12 harvested histomorphometric hypertrophic hz igf2 irradiated irradiation leaving limbs microarrays microdissection morphogenetic parathyroid plate plates pthr1 pz radio radiorecovery return tibia zone zones	begin differentially dige enolase failures gondii gra7 hypothetical imc1 mic2 naturally parasite proteomics pyrimethamine qrt rh rhoptry rop2 rop2a spectrometer spots strains sulfadiazine sulfonamide tga tgh toxoplasma toxoplasmosis undertook
Tagcloud (Difference) ?		17beta chondrocyte chondrocytes connective ctgf cxcl12 harvested histomorphometric hypertrophic hz igf2 irradiated irradiation leaving limbs microarrays microdissection morphogenetic parathyroid plate plates pthr1 pz radio radiorecovery return tibia zone zones	begin differentially dige enolase failures gondii gra7 hypothetical imc1 mic2 naturally parasite proteomics pyrimethamine qrt rh rhoptry rop2 rop2a spectrometer spots strains sulfadiazine sulfonamide tga tgh toxoplasma toxoplasmosis undertook
Tagcloud (Intersection) ?