IL17B and IL17RB

Number of citations of the paper that reports this interaction (PMID 10749887)
29

Data Source:
HPRD (in vivo, in vitro)

		IL17B	IL17RB
Gene Name		interleukin 17B	interleukin 17 receptor B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Cytokine Activity	Cytokine Receptor Activity Interleukin-17 Receptor Activity
	Biological Process	Inflammatory Response Immune Response Cell-cell Signaling Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Regulation Of Cell Growth Defense Response Cytokine-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ENO2 IL17RB UBC	4 interactors: IL17B IL25 RPS6KA5 TRAF6
Entrez ID		27190	55540
HPRD ID		05217	05677
Ensembl ID		ENSG00000127743	ENSG00000056736
Uniprot IDs		Q9UHF5	Q9NRM6
PDB IDs
Enriched GO Terms of Interacting Partners?		Glucose Metabolic Process Carbohydrate Biosynthetic Process Pathogenesis Hexose Metabolic Process Monosaccharide Metabolic Process Generation Of Precursor Metabolites And Energy Cytokine-mediated Signaling Pathway Viral Protein Processing Cellular Response To Cytokine Stimulus Response To Cytokine Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Carbohydrate Metabolic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Gluconeogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Hexose Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint	Interleukin-1-mediated Signaling Pathway Immune Response Defense Response Inflammatory Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Cellular Response To Interleukin-1 Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Cytokine Production Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Immune System Process Response To Interleukin-1 Positive Regulation Of Protein Phosphorylation Toll-like Receptor Signaling Pathway Myeloid Leukocyte Differentiation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Histone H2A-S1 Phosphorylation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Phosphorylation Activation Of Innate Immune Response Positive Regulation Of Protein Modification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Innate Immune Response Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway MAPK Cascade Positive Regulation Of Protein Metabolic Process Histone H3-S10 Phosphorylation Eosinophil Differentiation Regulation Of Innate Immune Response Myeloid Cell Differentiation Regulation Of Phosphorylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone Phosphorylation Signal Transduction By Phosphorylation Regulation Of Phosphorus Metabolic Process
Tagcloud ?		17beta chondrocyte chondrocytes connective ctgf cxcl12 harvested histomorphometric hypertrophic hz igf2 irradiated irradiation leaving limbs microarrays microdissection morphogenetic parathyroid plate plates pthr1 pz radio radiorecovery return tibia zone zones	affymetrix array beadarray characterizes coefficient computing correlate correlations cpg datasets decreases discretization discretized dlc1 epigenome genic global goldengate hypomethylation igf1r matching methylation mm myeloma p16 parameter pearson platforms utilized
Tagcloud (Difference) ?		17beta chondrocyte chondrocytes connective ctgf cxcl12 harvested histomorphometric hypertrophic hz igf2 irradiated irradiation leaving limbs microarrays microdissection morphogenetic parathyroid plate plates pthr1 pz radio radiorecovery return tibia zone zones	affymetrix array beadarray characterizes coefficient computing correlate correlations cpg datasets decreases discretization discretized dlc1 epigenome genic global goldengate hypomethylation igf1r matching methylation mm myeloma p16 parameter pearson platforms utilized
Tagcloud (Intersection) ?