DAPP1 and HSD3B7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DAPP1	HSD3B7
Gene Name		dual adaptor of phosphotyrosine and 3-phosphoinositides	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane	Cellular_component Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Phospholipid Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity
	Biological Process	Protein Dephosphorylation Signal Transduction	Bile Acid Biosynthetic Process Bile Acid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Signaling by the B Cell Receptor (BCR) Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System	Bile acid and bile salt metabolism Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 27-hydroxycholesterol Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts
Drugs		Inositol 1,3,4,5-Tetrakisphosphate
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BTK ERBB3 FCHSD2 HSD3B7 HSPA1A LCK LYN MAP4K1 PLCG1 PLCG2 RPL23 SRC	11 interactors: DAPP1 ICAM1 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 NOTCH2NL PYGL SPRY2
Entrez ID		27071	80270
HPRD ID		05773	09680
Ensembl ID		ENSG00000070190	ENSG00000099377
Uniprot IDs		B4DW38 Q9UN19	Q9H2F3
PDB IDs		1FAO 1FB8
Enriched GO Terms of Interacting Partners?		Fc Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Antigen Receptor-mediated Signaling Pathway Regulation Of Ion Homeostasis Regulation Of Immune System Process Innate Immune Response Protein Autophosphorylation Regulation Of Immune Response Positive Regulation Of Immune System Process Viral Process Peptidyl-tyrosine Phosphorylation Wound Healing Positive Regulation Of Immune Response Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Positive Regulation Of Protein Phosphorylation Immune Response Defense Response Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Intracellular Signal Transduction Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Response To Fibroblast Growth Factor Stimulus Response To Stress Regulation Of Cell Death Platelet Activation Response To Fibroblast Growth Factor Positive Regulation Of Kinase Activity Peptidyl-amino Acid Modification Neurotrophin TRK Receptor Signaling Pathway Response To Organic Substance Neurotrophin Signaling Pathway Leukocyte Migration Positive Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Regulation Of Body Fluid Levels	Response To Sulfur Dioxide Positive Regulation Of ERK1 And ERK2 Cascade T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Sensory Perception Of Sound Sensory Perception Of Mechanical Stimulus Regulation Of ERK1 And ERK2 Cascade Glucose Homeostasis 5-phosphoribose 1-diphosphate Biosynthetic Process Receptor-mediated Virion Attachment To Host Cell T Cell Antigen Processing And Presentation Membrane To Membrane Docking Positive Regulation Of Cellular Extravasation Establishment Of Sertoli Cell Barrier Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Virion Attachment To Host Cell Lung Growth Acute Inflammatory Response To Antigenic Stimulus Regulation Of Neurotrophin TRK Receptor Signaling Pathway Adhesion Of Symbiont To Host Bud Elongation Involved In Lung Branching Regulation Of Cellular Amino Acid Metabolic Process Cell Adhesion Mediated By Integrin Positive Regulation Of MAPK Cascade Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Ruffle Assembly Negative Regulation Of Ras GTPase Activity Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Polysaccharide Catabolic Process Sertoli Cell Development Response To Copper Ion Regulation Of Ras GTPase Activity
Tagcloud ?		abat accuracy biomarkers bisulfite cloning diagnosis differential downregulated draft fadd hematologic hypermethylated hypermethylation lrrfip1 mds methylation microarray myelodysplastic noninvasive patterns plbd1 profiles refined screened sequencing smpd3 specificity validate validation
Tagcloud (Difference) ?		abat accuracy biomarkers bisulfite cloning diagnosis differential downregulated draft fadd hematologic hypermethylated hypermethylation lrrfip1 mds methylation microarray myelodysplastic noninvasive patterns plbd1 profiles refined screened sequencing smpd3 specificity validate validation
Tagcloud (Intersection) ?