GJB3 and CNST

Number of citations of the paper that reports this interaction (PubMedID 19864490)
62

Data Source:
BioGRID (pull down)

		GJB3	CNST
Description		gap junction protein beta 3	consortin, connexin sorting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell-cell Junction Gap Junction Connexin Complex Membrane Cell Junction Anchoring Junction	Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	Gap Junction Channel Activity Protein Binding	Protein Binding Phosphatase Binding Connexin Binding
	Biological Process	Placenta Development Cell Communication Cell-cell Signaling Transmembrane Transport	Positive Regulation Of Golgi To Plasma Membrane Protein Transport
Pathways		Gap junction assembly Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases		Deafness, autosomal recessive Erythrokeratodermia variabilis Deafness, autosomal dominant
GWAS		Intraocular pressure ( 30591961) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Antisaccade task score ( 31596458)
Interacting Genes		15 interacting genes: BTN2A2 CNST COMT ELAVL1 GIMAP5 IGFBP5 LAT LHFPL5 MFSD11 RPRM SERP1 TJP1 TMEM97 TMUB2 TRARG1	13 interacting genes: EWSR1 GJA1 GJB1 GJB2 GJB3 GJB6 GJC1 PIGP POT1 PPP1CA PPP1CC ROPN1 SNCA
Entrez ID		2707	163882
HPRD ID		04505	08718
Ensembl ID		ENSG00000188910	ENSG00000162852
Uniprot IDs		O75712	Q6PJW8
PDB IDs
Enriched GO Terms of Interacting Partners?			Connexin Complex Gap Junction Channel Activity Gap Junction Assembly Gap Junction Cell Communication By Electrical Coupling Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling Cell-cell Junction Assembly Cell-cell Signaling Cell-cell Junction Organization Signaling Cell Communication Anchoring Junction Cell Junction Organization Cell Junction Assembly Gap Junction-mediated Intercellular Transport PTW/PP1 Phosphatase Complex Cardiac Muscle Tissue Development Atrial Cardiac Muscle Cell Action Potential Intercellular Transport Presynapse Cell Communication By Electrical Coupling Involved In Cardiac Conduction Striated Muscle Tissue Development Cell Communication Involved In Cardiac Conduction Transmembrane Transport Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Cellular Component Assembly Muscle Tissue Development Photoperiodism Entrainment Of Circadian Clock Maintenance Of Blood-brain Barrier Chromosome, Telomeric Region Cardiac Muscle Cell Action Potential Involved In Contraction Response To Electrical Stimulus Cardiac Muscle Cell Action Potential Beta-tubulin Binding Cell Junction Alpha-tubulin Binding Kinesin Binding Intercalated Disc Postsynapse Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Glycogen Metabolic Process
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