GHITM and CCSER2

		GHITM	CCSER2
Description		growth hormone inducible transmembrane protein	coiled-coil serine rich protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane Extracellular Exosome	Cytoplasm Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Calcium Channel Activity Protein Binding Calcium:proton Antiporter Activity	Protein Binding Microtubule Binding
	Biological Process	Calcium Ion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Inner Mitochondrial Membrane Organization Negative Regulation Of Release Of Cytochrome C From Mitochondria Calcium Export From The Mitochondrion Mitochondrial Potassium Ion Transmembrane Transport Proton Transmembrane Transport Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport	Microtubule Bundle Formation
Pathways
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Influenza A (H1N1) infection ( 26379185) Metabolite levels ( 23823483) Mild influenza (H1N1) infection ( 26379185) Refractive error ( 32231278)	Cerebrospinal P-tau181p levels ( 28247064) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Refractive error ( 32231278)
Interacting Genes		13 interacting genes: AGTR1 CCR4 DRD2 FAM209A FXYD3 GPR35 GPR37 HTR2C HTR4 JSRP1 PGRMC2 SLC22A1 TMEM242	12 interacting genes: APP ATRX CRADD EXOC1 EXOSC8 GTF2H1 KIFAP3 MAP1LC3B OFD1 PSMD11 STX1A TCEA2
Entrez ID		27069	54462
HPRD ID		17038	13832
Ensembl ID		ENSG00000165678	ENSG00000107771
Uniprot IDs		Q9H3K2	Q9H7U1
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Renal Sodium Excretion Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Catecholamine Uptake Dopamine Uptake Serotonin Binding Serotonin Receptor Signaling Pathway Serotonin Receptor Activity Monoatomic Cation Transport G Protein-coupled Serotonin Receptor Activity Interneuron Migration Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Calcium Ion Transmembrane Import Into Cytosol Set1C/COMPASS Complex Neurotransmitter Receptor Activity Dopamine Transport Neurotransmitter Reuptake Monoatomic Ion Transport G Protein-coupled Serotonin Receptor Signaling Pathway Chemokine Receptor Activity Metal Ion Transport Regulation Of Appetite Regulation Of Sequestering Of Calcium Ion Monoamine Transport Neurotransmitter Uptake Dopamine Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Monoatomic Ion Transmembrane Transport Angiotensin Type I Receptor Activity Calcium Ion Transmembrane Transport Catecholamine Metabolic Process Large Intestinal Transit Dendrite Membrane G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Intracellular Signaling Cassette Bradykinin Receptor Binding G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Calcium Ion Transport Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Prosaposin Receptor Activity 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding (R)-carnitine Transmembrane Transport Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein-containing Complex Organization Axo-dendritic Transport Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Microtubule-based Transport Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cellular Component Assembly Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Protein-containing Complex Assembly Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Modulation Of Excitatory Postsynaptic Potential Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric Post-embryonic Forelimb Morphogenesis Chromosome, Subtelomeric Region Vesicle Docking Involved In Exocytosis Membrane Docking Myosin Head/neck Binding Vesicle Docking Positive Regulation Of Norepinephrine Secretion Organelle Localization By Membrane Tethering Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Ciliary Basal Body Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Death Domain Binding Endopeptidase Complex U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Kinesin II Complex Positive Regulation Of Calcium-dependent Cell-cell Adhesion Calcium:proton Antiporter Activity Calcium Export From The Mitochondrion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Microtubule-based Process Regulation Of Apoptotic Signaling Pathway
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