GHITM and JSRP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GHITM	JSRP1
Description		growth hormone inducible transmembrane protein	junctional sarcoplasmic reticulum protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane
	Molecular Function	Calcium Channel Activity Protein Binding Calcium:proton Antiporter Activity	Protein Binding
	Biological Process	Calcium Ion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Inner Mitochondrial Membrane Organization Negative Regulation Of Release Of Cytochrome C From Mitochondria Calcium Export From The Mitochondrion Mitochondrial Potassium Ion Transmembrane Transport Proton Transmembrane Transport Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport	Skeletal Muscle Contraction
Pathways
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Influenza A (H1N1) infection ( 26379185) Metabolite levels ( 23823483) Mild influenza (H1N1) infection ( 26379185) Refractive error ( 32231278)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		13 interacting genes: AGTR1 CCR4 DRD2 FAM209A FXYD3 GPR35 GPR37 HTR2C HTR4 JSRP1 PGRMC2 SLC22A1 TMEM242	9 interacting genes: CDS2 GHITM LAT MS4A13 SLC30A8 STX8 TERF1 TMBIM6 UBQLN1
Entrez ID		27069	126306
HPRD ID		17038	08724
Ensembl ID		ENSG00000165678	ENSG00000167476
Uniprot IDs		Q9H3K2	Q96MG2
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Renal Sodium Excretion Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Catecholamine Uptake Dopamine Uptake Serotonin Binding Serotonin Receptor Signaling Pathway Serotonin Receptor Activity Monoatomic Cation Transport G Protein-coupled Serotonin Receptor Activity Interneuron Migration Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Calcium Ion Transmembrane Import Into Cytosol Set1C/COMPASS Complex Neurotransmitter Receptor Activity Dopamine Transport Neurotransmitter Reuptake Monoatomic Ion Transport G Protein-coupled Serotonin Receptor Signaling Pathway Chemokine Receptor Activity Metal Ion Transport Regulation Of Appetite Regulation Of Sequestering Of Calcium Ion Monoamine Transport Neurotransmitter Uptake Dopamine Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Monoatomic Ion Transmembrane Transport Angiotensin Type I Receptor Activity Calcium Ion Transmembrane Transport Catecholamine Metabolic Process Large Intestinal Transit Dendrite Membrane G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Intracellular Signaling Cassette Bradykinin Receptor Binding G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Calcium Ion Transport Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Prosaposin Receptor Activity 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding (R)-carnitine Transmembrane Transport Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity	Calcium Channel Activity Endoribonuclease Inhibitor Activity Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transmembrane Transport Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Shelterin Complex Assembly Phosphatidate Cytidylyltransferase Activity TCR Signalosome Calcium:proton Antiporter Activity Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Monoatomic Ion Transport Response To Type II Interferon Negative Regulation Of Transmembrane Transport Organelle Localization Calcium Export From The Mitochondrion Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Mitochondrial Potassium Ion Transmembrane Transport Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Negative Regulation Of Calcium Ion Transport Into Cytosol Monoatomic Cation Transmembrane Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Shelterin Complex Ankyrin Repeat Binding Phosphatidylglycerol Biosynthetic Process Chloride Channel Inhibitor Activity Membrane Raft Distribution Zinc Ion Import Across Plasma Membrane Zinc:proton Antiporter Activity Membrane Membrane Organization Regulation Of Intrinsic Apoptotic Signaling Pathway Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Membrane Raft Localization
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