STAU2 and DHX58

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (pull down)

		STAU2	DHX58
Gene Name		staufen double-stranded RNA binding protein 2	DEXH (Asp-Glu-X-His) box polypeptide 58
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Endoplasmic Reticulum Microtubule Membrane	Cytoplasm
	Molecular Function	Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding	DNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding
	Biological Process	Transport	Metabolic Process Response To Virus Viral Process Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: DHX58 KIAA1377	9 interactors: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2
Entrez ID		27067	79132
HPRD ID		09328	13115
Ensembl ID		ENSG00000040341	ENSG00000108771
Uniprot IDs		A8K276 E9PH62 F8VPI7 Q4LE57 Q9NUL3	Q96C10
PDB IDs			2RQA 2W4R 3EQT
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MDA-5 Signaling Pathway Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of Viral-induced Cytoplasmic Pattern Recognition Receptor Signaling Pathway Regulation Of RIG-I Signaling Pathway Negative Regulation Of Defense Response To Virus Negative Regulation Of Innate Immune Response Cytoplasmic Microtubule Organization Negative Regulation Of Type I Interferon Production Mitotic Spindle Organization Positive Regulation Of Type I Interferon Production Regulation Of Defense Response To Virus Regulation Of Type I Interferon Production Negative Regulation Of Immune Response Spindle Organization	RNA Interference Pre-miRNA Processing Posttranscriptional Regulation Of Gene Expression Production Of MiRNAs Involved In Gene Silencing By MiRNA Ribonucleoprotein Complex Assembly Regulation Of Defense Response To Virus By Virus RNA Processing Gene Expression Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Regulation Of Translation Ribonucleoprotein Complex Biogenesis Gene Silencing By RNA Regulation Of Viral Genome Replication RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of Translational Initiation Response To DsRNA Regulation Of Epidermal Growth Factor Receptor Signaling Pathway RNA Metabolic Process Evasion Or Tolerance By Virus Of Host Immune Response Conversion Of Ds SiRNA To Ss SiRNA Involved In RNA Interference Hair Follicle Cell Proliferation Conversion Of Ds SiRNA To Ss SiRNA Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Negative Regulation Of Translation Negative Regulation Of Cellular Metabolic Process Immune System Process Gene Silencing RNA Phosphodiester Bond Hydrolysis MRNA Cleavage Involved In Gene Silencing By MiRNA Regulation Of Enamel Mineralization Peripheral Nervous System Myelin Formation Synaptic Growth At Neuromuscular Junction Zygote Asymmetric Cell Division Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Gene Expression Defense Response Negative Regulation Of Biosynthetic Process SiRNA Loading Onto RISC Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Notch Signaling Pathway Post-embryonic Development Cellular Macromolecular Complex Assembly Regulation Of Viral Process Neuron Projection Morphogenesis Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
Tagcloud ?		associate dendrites dendritic depleted dhpg dissociation granules ltd ltp map1b map2 mglur miniature p0 plasticity potentiation prevents pyramidal reduces ribonucleoprotein ribosomal spine spines stau1 staufen synaptic transcript unexplored unlike
Tagcloud (Difference) ?		associate dendrites dendritic depleted dhpg dissociation granules ltd ltp map1b map2 mglur miniature p0 plasticity potentiation prevents pyramidal reduces ribonucleoprotein ribosomal spine spines stau1 staufen synaptic transcript unexplored unlike
Tagcloud (Intersection) ?