NPTN and SURF2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		NPTN	SURF2
Gene Name		neuroplastin	surfeit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Surface Integral Component Of Membrane Presynaptic Membrane	Cellular_component Nucleus Nucleolus Plasma Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Type 1 Fibroblast Growth Factor Receptor Binding ATP Binding Cell Adhesion Molecule Binding	Molecular_function
	Biological Process	Positive Regulation Of Protein Phosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Neuron Projection Development Peptidyl-tyrosine Phosphorylation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Long-term Synaptic Potentiation	Biological_process
Pathways
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881)
Protein-Protein Interactions		1 interactors: SURF2	7 interactors: APP B4GALT3 NPTN PLAUR PRNP RPL5 ZNF331
Entrez ID		27020	6835
HPRD ID		18033	15948
Ensembl ID		ENSG00000156642	ENSG00000148291
Uniprot IDs		F5GYM7 Q9Y639	Q15527
PDB IDs
Enriched GO Terms of Interacting Partners?			Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Urokinase Plasminogen Activator Signaling Pathway Cellular Chemical Homeostasis Ion Homeostasis Chemotaxis Synaptic Growth At Neuromuscular Junction Transition Metal Ion Homeostasis Cellular Homeostasis Collateral Sprouting In Absence Of Injury Negative Regulation Of Calcineurin-NFAT Signaling Cascade Collateral Sprouting Axon Midline Choice Point Recognition Post-translational Protein Modification Chemical Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Copper Ion Axon Choice Point Recognition Negative Regulation Of Calcium-mediated Signaling Regulation Of Protein Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Learning Or Memory Neuron Remodeling Negative Regulation Of Interleukin-17 Production Regulation Of Protein Phosphorylation Regulation Of Calcineurin-NFAT Signaling Cascade Cognition Cellular Calcium Ion Homeostasis Cellular Protein Metabolic Process Calcium Ion Homeostasis Attachment Of GPI Anchor To Protein Negative Regulation Of Activated T Cell Proliferation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Locomotion Regulation Of Phosphorylation Axon Guidance Negative Regulation Of Interleukin-2 Production Homeostatic Process Negative Regulation Of T Cell Receptor Signaling Pathway Response To Oxidative Stress Blood Coagulation Hemostasis Response To Copper Ion Suckling Behavior Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component
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