NPTN

Description		neuroplastin
Image
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Cell Surface Postsynaptic Density Membrane Axon Dendrite Presynaptic Membrane Synapse
	Molecular Function	Type 1 Fibroblast Growth Factor Receptor Binding Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Protein Phosphorylation Intracellular Calcium Ion Homeostasis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Synapse Organization Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Metabolic Process Long-term Synaptic Potentiation Dendrite Self-avoidance Regulation Of Receptor Localization To Synapse Excitatory Synapse Assembly
Pathways		GABA receptor activation
Drugs
Diseases
GWAS		Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications ( 28100913) Tourette syndrome ( 30818990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		1 novel interacting genes: AATF
Interacting Genes		3 interacting genes: AGTR1 SURF2 UBC
Entrez ID		27020
HPRD ID		18033
Ensembl ID		ENSG00000156642
Uniprot IDs		Q9Y639
PDB IDs		6A69
Enriched GO Terms of Interacting Partners?		Angiotensin Type I Receptor Activity Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Renal Sodium Excretion Embryonic Cleavage Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Leucine Zipper Domain Binding Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Macrophage Derived Foam Cell Differentiation Angiotensin-activated Signaling Pathway Low-density Lipoprotein Particle Remodeling Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Protein Tag Activity Negative Regulation Of Glycoprotein Metabolic Process Negative Regulation Of Glycoprotein Biosynthetic Process Regulation Of Amyloid Precursor Protein Biosynthetic Process Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Positive Regulation Of Cholesterol Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation
Tagcloud ?