GGT7 and LHFPL5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GGT7	LHFPL5
Gene Name		gamma-glutamyltransferase 7	lipoma HMGIC fusion partner-like 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Anchored Component Of External Side Of Plasma Membrane	Integral Component Of Membrane Apical Plasma Membrane Stereocilium Bundle Tip
	Molecular Function	Gamma-glutamyltransferase Activity Glutathione Hydrolase Activity
	Biological Process	Proteolysis Glutathione Metabolic Process Glutathione Biosynthetic Process Leukotriene Biosynthetic Process	Ion Transport Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Auditory Receptor Cell Stereocilium Organization
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Aflatoxin activation and detoxification Glutathione synthesis and recycling Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Glutathione conjugation Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FAM57A GPR25 LHFPL5 MALL TMEM242	2 interactors: CCDC155 GGT7
Entrez ID		2686	222662
HPRD ID		07488	13989
Ensembl ID		ENSG00000131067	ENSG00000197753
Uniprot IDs		A0PJJ9 Q9UJ14	B3KX66 Q8TAF8
PDB IDs
Enriched GO Terms of Interacting Partners?		Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Auditory Receptor Cell Development Inner Ear Receptor Stereocilium Organization Auditory Receptor Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Hair Cell Differentiation Inner Ear Receptor Cell Development Detection Of Mechanical Stimulus Inner Ear Receptor Cell Differentiation	Chromosome Localization To Nuclear Envelope Involved In Synapsis Leukotriene Biosynthetic Process Glutathione Biosynthetic Process Peptide Biosynthetic Process Leukotriene Metabolic Process Establishment Of Chromosome Localization Icosanoid Biosynthetic Process Synapsis Homologous Chromosome Segregation Unsaturated Fatty Acid Biosynthetic Process Glutathione Metabolic Process Oogenesis Double-strand Break Repair Via Homologous Recombination Meiotic Chromosome Segregation Recombinational Repair Icosanoid Metabolic Process Meiosis I Unsaturated Fatty Acid Metabolic Process Female Gamete Generation Fatty Acid Biosynthetic Process Double-strand Break Repair Peptide Metabolic Process Meiotic Nuclear Division
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