AATF and ZNF468

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AATF	ZNF468
Gene Name		apoptosis antagonizing transcription factor	zinc finger protein 468
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Golgi Apparatus Centrosome Focal Adhesion	Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Leucine Zipper Domain Binding Poly(A) RNA Binding Tau Protein Binding	DNA Binding Metal Ion Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Reactive Oxygen Species Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK p75 NTR receptor-mediated signalling	Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		26 interactors: ATM ATR CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MPP6 NEDD4L NGDN PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468	2 interactors: AATF SLC9A3R1
Entrez ID		26574	90333
HPRD ID		12236	18344
Ensembl ID		ENSG00000108270	ENSG00000204604
Uniprot IDs		Q9NY61	Q5VIY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Replicative Senescence Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression DNA Damage Induced Protein Phosphorylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Biosynthetic Process Cell Aging Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Apoptotic Signaling Pathway RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Protein Catabolic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cell Cycle Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Programmed Cell Death Negative Regulation Of Cell Cycle Cell Cycle Process Cell Death Death Regulation Of Mitotic Nuclear Division Response To Abiotic Stimulus Cell Differentiation Regulation Of Cell Proliferation Gene Expression Developmental Process Transforming Growth Factor Beta Receptor Signaling Pathway	Renal Phosphate Ion Absorption Glutathione Transport Negative Regulation Of Sodium:proton Antiporter Activity Renal Sodium Ion Transport Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Superoxide Anion Generation Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Amyloid Precursor Protein Biosynthetic Process Phospholipase C-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Cell Death Bile Acid Secretion Oligopeptide Transport Embryonic Cleavage Negative Regulation Of Glycoprotein Metabolic Process Negative Regulation Of Sodium Ion Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Renal Absorption Regulation Of Proton Transport Phosphate Ion Homeostasis Regulation Of Superoxide Anion Generation Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Excretion Regulation Of Glycoprotein Biosynthetic Process Regulation Of Sodium Ion Transmembrane Transporter Activity Bile Acid And Bile Salt Transport Dopamine Receptor Signaling Pathway Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Transporter Activity Negative Regulation Of Reactive Oxygen Species Metabolic Process Anion Homeostasis Regulation Of Apoptotic Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Cell Death Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Transmembrane Transport Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Acid Secretion Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Sodium Ion Transport
Tagcloud ?		accuracy balb behavioral biomarker circadian comprising cooperativity crucial directed encoded exists explore fact forensic governs hence investigation keeping metabolism microrna mortem pmi reasonably rhythm rhythmicity rnome turn unambiguously view
Tagcloud (Difference) ?		accuracy balb behavioral biomarker circadian comprising cooperativity crucial directed encoded exists explore fact forensic governs hence investigation keeping metabolism microrna mortem pmi reasonably rhythm rhythmicity rnome turn unambiguously view
Tagcloud (Intersection) ?