AATF and MYO1D

		AATF	MYO1D
Description		apoptosis antagonizing transcription factor	myosin ID
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Small-subunit Processome	Cytoplasm Endosome Early Endosome Plasma Membrane Microvillus Brush Border Cell Cortex Actin Cytoskeleton Basolateral Plasma Membrane Myosin Complex Axon Dendrite Axolemma Cytoplasmic Vesicle Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Myelin Sheath Extracellular Exosome Apical Dendrite
	Molecular Function	RNA Binding Protein Binding Leucine Zipper Domain Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Calcium-dependent Protein Binding Actin Filament Binding
	Biological Process	Cell Adhesion Regulation Of Mitotic Cell Cycle Embryonic Cleavage Ribosome Biogenesis Ribosomal Small Subunit Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Signaling Pathway	Endocytosis Actin Filament Organization Protein Transport Actin Filament-based Movement Cellular Localization Early Endosome To Recycling Endosome Transport
Pathways		NRAGE signals death through JNK
Drugs
Diseases
GWAS		Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661) Thyroid volume in Hashimoto’s thyroiditis ( 32019955)	Anorexia nervosa ( 29155802) Emotional recognition ( 32366958) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hypertension risk in short sleep duration ( 22322875) Immature fraction of reticulocytes ( 32888494 27863252) Local histogram emphysema pattern ( 25006744) Myopia ( 27182965) Neurofibrillary tangles ( 25188341) Pancreatic cancer ( 20686608) Red cell distribution width ( 32888494 27863252) Refractive error ( 32231278 23396134) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		29 interacting genes: ATM ATR AURKA CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MYCBP2 NEDD4L PALS2 PARP1 PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468	4 interacting genes: H19 PTEN RPL37 TFIP11
Entrez ID		26574	4642
HPRD ID		12236	07581
Ensembl ID		ENSG00000275700	ENSG00000176658
Uniprot IDs		A0A7P0TAR0 A0A7P0TBG4 Q9NY61	J3KRL0 J3QRN6 K7EIG7 O94832 Q8N618
PDB IDs		5W6A 7MQ8 7MQ9
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Regulation Of Protein Metabolic Process Replicative Senescence Positive Regulation Of Metabolic Process Response To Gamma Radiation Regulation Of Cell Communication Regulation Of Signaling Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Cellular Response To Oxygen-containing Compound Regulation Of Signal Transduction Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Component Organization Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Regulation Of Organelle Organization Negative Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Programmed Cell Death PML Body Chromatin Organization Establishment Of RNA Localization To Telomere Establishment Of Protein-containing Complex Localization To Telomere Regulation Of Mitotic Nuclear Division Regulation Of Cellular Response To Heat Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomerase Catalytic Core Complex Assembly G2/M Transition Of Mitotic Cell Cycle Regulation Of Developmental Process Regulation Of Anatomical Structure Morphogenesis Protein Serine Kinase Activity Negative Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Protein Kinase Activity Cell Cycle G2/M Phase Transition Apoptotic Process Protein Homodimerization Activity Positive Regulation Of Cellular Component Organization Regulation Of Protein Stability Regulation Of Protein Catabolic Process Nucleoplasm Programmed Cell Death	Locomotor Rhythm Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Spindle Assembly Involved In Female Meiosis Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Negative Regulation Of Cell Size Presynaptic Membrane Organization Schmidt-Lanterman Incisure Rhythmic Synaptic Transmission Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity MDM2/MDM4 Family Protein Binding Ubiquitin Ligase Inhibitor Activity Vesicle Tethering To Endoplasmic Reticulum Endoplasmic Reticulum-endosome Membrane Contact Site Organelle Membrane Contact Site C21-steroid Hormone Biosynthetic Process Progesterone Biosynthetic Process Spliceosomal Complex Disassembly Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Protection From Non-homologous End Joining At Telomere U2-type Post-mRNA Release Spliceosomal Complex Embryonic Cleavage Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Leucine Zipper Domain Binding Phosphatidylinositol-3-phosphate Phosphatase Activity Prepulse Inhibition Maternal Behavior Progesterone Metabolic Process Telomere Maintenance In Response To DNA Damage Negative Regulation Of Glycoprotein Biosynthetic Process Lipid Binding Meiotic Spindle Assembly Synapse Maturation
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