DAZAP1 and PRMT2

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		DAZAP1	PRMT2
Description		DAZ associated protein 1	protein arginine methyltransferase 2
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GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding RNA Stem-loop Binding	Transcription Coactivator Activity Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Transferase Activity Nuclear Estrogen Receptor Binding Nuclear Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Nuclear Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Nuclear Thyroid Hormone Receptor Binding Nuclear Androgen Receptor Binding Histone H3R8 Methyltransferase Activity Histone H3 Methyltransferase Activity
	Biological Process	Maternal Placenta Development Spermatogenesis Cell Differentiation Positive Regulation Of MRNA Splicing, Via Spliceosome Fibroblast Proliferation	Chromatin Remodeling Regulation Of DNA-templated Transcription Protein Methylation Signal Transduction Negative Regulation Of NF-kappaB Transcription Factor Activity Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Developmental Cell Growth Negative Regulation Of Inflammatory Response Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Pulse pressure ( 30224653) Reading and spelling ( 23738518) Word reading ( 23738518)	Diverticular disease ( 30177863)
Interacting Genes		7 interacting genes: CEBPA DAZ1 DAZL ITCH OGT PRMT2 SNRPA	37 interacting genes: BAG6 CBLB CHEK2 CPSF7 DAZAP1 DMRTB1 ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 IQSEC2 KDM6B MYO6 NCOA1 NCOA6 PGR PRMT8 PRRC2A PSMB3 R3HDM1 RB1 RBM12 RBM22 RIPK2 RXRA SHANK1 SHANK3 SHTN1 SPAG8 THRB WASL WBP11 YLPM1 ZFP36 ZNF341 ZSWIM8
Entrez ID		26528	3275
HPRD ID		08462	09060
Ensembl ID		ENSG00000071626	ENSG00000160310
Uniprot IDs		A0A0S2Z569 K7EK33 K7EQ55 Q96EP5	A0A0S2Z3N3 P55345
PDB IDs		2DGS 2DH8	1X2P
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translational Initiation Positive Regulation Of Protein Metabolic Process Protein-containing Complex Regulation Of Translational Initiation Translation Activator Activity Positive Regulation Of Translation 3'-UTR-mediated MRNA Stabilization Regulation Of Necroptotic Process Regulation Of Programmed Necrotic Cell Death Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Stabilization Histone H3R8 Methyltransferase Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Positive Regulation Of Macromolecule Metabolic Process Chromatin DNA Binding Response To Vitamin B2 C/EBP Complex Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Negative Regulation Of RNA Catabolic Process Female Meiosis II Negative Regulation Of Canonical NF-kappaB Signal Transduction Nuclear Progesterone Receptor Binding Positive Regulation Of Metabolic Process CHOP-C/EBP Complex Positive Regulation Of Gene Expression Cytoplasmic Translation Protein O-acetylglucosaminyltransferase Activity Inflammatory Response MRNA 3'-UTR Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process White Fat Cell Proliferation Nucleic Acid Binding Spliceosomal SnRNP Complex T Cell Anergy Response To Nutrient Cell Maturation Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex	Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Enzyme Binding Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Receptor-mediated Signaling Pathway Nuclear Receptor Activity Positive Regulation Of Biosynthetic Process Nuclear Steroid Receptor Activity Nucleus Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process MRNA Metabolic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Hormone-mediated Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Estrogen Response Element Binding Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Dendritic Spine Morphogenesis Nucleic Acid Metabolic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Estrogen Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Estrogen Receptor Activity Synaptic Receptor Adaptor Activity Regulation Of Transcription By RNA Polymerase II Steroid Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Dendritic Spine Organization RNA Binding Nuclear Estrogen Receptor Binding Neuron Projection Organization Postsynapse Organization Regulation Of Female Receptivity Female Mating Behavior MRNA Transcription By RNA Polymerase II
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