DAZAP1 and DAZL

Number of citations of the paper that reports this interaction (PubMedID 29395067)
0

Data Source:
BioGRID (proximity labelling technology, pull down)
HPRD (in vitro)

		DAZAP1	DAZL
Description		DAZ associated protein 1	deleted in azoospermia like
Image			No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Ribonucleoprotein Complex	Nucleus Cytoplasm Ribosome Protein-containing Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding RNA Stem-loop Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity Identical Protein Binding
	Biological Process	Maternal Placenta Development Spermatogenesis Cell Differentiation Positive Regulation Of MRNA Splicing, Via Spliceosome Fibroblast Proliferation	Oocyte Maturation Regulation Of Translation Female Meiosis II Germ Cell Development Spermatogenesis Cell Differentiation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Translational Initiation 3'-UTR-mediated MRNA Stabilization
Pathways
Drugs
Diseases
GWAS		Pulse pressure ( 30224653) Reading and spelling ( 23738518) Word reading ( 23738518)	Feeling fed-up ( 29500382) Intelligence ( 28530673) Lung cancer ( 28604730) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Smoking initiation ( 33082346) Testicular germ cell tumor ( 23666240 25877299 28604728 28604732)
Interacting Genes		7 interacting genes: CEBPA DAZ1 DAZL ITCH OGT PRMT2 SNRPA	5 interacting genes: DAZ1 DAZ4 DAZAP1 DAZAP2 PUM2
Entrez ID		26528	1618
HPRD ID		08462	09029
Ensembl ID		ENSG00000071626	ENSG00000092345
Uniprot IDs		A0A0S2Z569 K7EK33 K7EQ55 Q96EP5	A0A140VK77 Q92904
PDB IDs		2DGS 2DH8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translational Initiation Positive Regulation Of Protein Metabolic Process Protein-containing Complex Regulation Of Translational Initiation Translation Activator Activity Positive Regulation Of Translation 3'-UTR-mediated MRNA Stabilization Regulation Of Necroptotic Process Regulation Of Programmed Necrotic Cell Death Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Stabilization Histone H3R8 Methyltransferase Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Positive Regulation Of Macromolecule Metabolic Process Chromatin DNA Binding Response To Vitamin B2 C/EBP Complex Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Negative Regulation Of RNA Catabolic Process Female Meiosis II Negative Regulation Of Canonical NF-kappaB Signal Transduction Nuclear Progesterone Receptor Binding Positive Regulation Of Metabolic Process CHOP-C/EBP Complex Positive Regulation Of Gene Expression Cytoplasmic Translation Protein O-acetylglucosaminyltransferase Activity Inflammatory Response MRNA 3'-UTR Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process White Fat Cell Proliferation Nucleic Acid Binding Spliceosomal SnRNP Complex T Cell Anergy Response To Nutrient Cell Maturation Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex	MRNA 3'-UTR Binding Regulation Of MRNA Metabolic Process Translation Activator Activity Regulation Of MRNA Stability Regulation Of RNA Stability 3'-UTR-mediated MRNA Stabilization Protein-containing Complex Stress Granule Assembly Positive Regulation Of Translational Initiation Regulation Of Translation MRNA Stabilization Male Gamete Generation Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Catabolic Process Spermatogenesis RNA Stabilization RNA Binding Gamete Generation Negative Regulation Of RNA Catabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Cytoplasmic Stress Granule Pumilio-response Element Binding Negative Regulation Of MRNA Metabolic Process Nucleic Acid Binding Regulation Of Translational Initiation Post-transcriptional Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Sprouting Of Injured Axon Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Translation Developmental Process Involved In Reproduction Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Intracellular MRNA Localization Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Biological Quality Poly(G) Binding Positive Regulation Of Biosynthetic Process Membraneless Organelle Assembly Positive Regulation Of Axon Regeneration Maternal Placenta Development Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of MiRNA-mediated Gene Silencing Reproductive Process Negative Regulation Of Catabolic Process Mitogen-activated Protein Kinase Kinase Kinase Binding
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