GNL3 and DNAH1

		GNL3	DNAH1
Description		G protein nucleolar 3	dynein axonemal heavy chain 1
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GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body Midbody	Extracellular Region Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Axoneme Dynein Complex Motile Cilium Sperm Flagellum Inner Dynein Arm Cell Projection
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding GTP Binding MRNA 5'-UTR Binding	Nucleotide Binding Microtubule Motor Activity ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Stem Cell Division Stem Cell Population Maintenance Positive Regulation Of Telomere Maintenance Positive Regulation Of Protein Sumoylation Regulation Of Cell Population Proliferation Positive Regulation Of MiRNA Transcription Positive Regulation Of Protein Localization To Chromosome, Telomeric Region	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Microtubule-based Movement Sperm Axoneme Assembly Flagellated Sperm Motility Inner Dynein Arm Assembly Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Bipolar disorder ( 21926972 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Iron status biomarkers (ferritin levels) ( 33536631) Osteoarthritis ( 22763110) Schizophrenia ( 29483656 28991256 25056061 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronotype ( 30696823) Electroencephalogram traits ( 25387704) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol ( 30275531) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: ANXA1 ASCC2 CEP19 DYSF ING4 MDM2 NPM1 OGT PPP2R5A PTEN STAT3 TP53 USP7 WEE2-AS1
Entrez ID		26354	25981
HPRD ID		06419	11790
Ensembl ID		ENSG00000163938	ENSG00000114841
Uniprot IDs		Q9BVP2	A0A140VJI6 Q9P2D7
PDB IDs		8FKP 8FKR 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8RL2	8I3J 8J07
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Phase Transition Cellular Response To Actinomycin D Regulation Of Cellular Component Organization Regulation Of G1/S Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Regulation Of Protein Stability Response To Actinomycin D Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Proteolysis Protein Localization To Nucleus Cellular Response To UV-C Negative Regulation Of Protein Metabolic Process Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Cellular Component Organization Negative Regulation Of MiRNA Processing Negative Regulation Of Gene Expression Regulation Of Cell Cycle Process Regulation Of Carbohydrate Catabolic Process Protein-containing Complex P53 Binding Cellular Response To Antibiotic DNA Alkylation Repair Cellular Component Assembly Protein Stabilization Regulation Of Purine Nucleotide Metabolic Process Nucleoplasm Cellular Response To UV Cellular Response To Nutrient Levels Rhythmic Process Response To UV-C Regulation Of MiRNA Processing Regulation Of Cellular Response To Stress Regulation Of Vesicle-mediated Transport Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of Regulatory NcRNA Processing Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Regulation Of Glucose Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Autophagy Cellular Response To Light Stimulus Core Promoter Sequence-specific DNA Binding PML Body Regulation Of Cell Communication	DNA/RNA Helicase Activity RNA Binding TRNA Processing Growth Plate Cartilage Chondrocyte Development Positive Regulation Of Centrosome Duplication Chondrocyte Development Involved In Endochondral Bone Morphogenesis Positive Regulation Of Protein Localization To Chromosome, Telomeric Region O-phosphoseryl-tRNA(Sec) Selenium Transferase Activity Conversion Of Seryl-tRNAsec To Selenocys-tRNAsec MPP7-DLG1-LIN7 Complex
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