GAP43 and CD47

		GAP43	CD47
Description		growth associated protein 43	CD47 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Axon Dendrite Filopodium Membrane Growth Cone Membrane Cell Projection Perikaryon Synapse Cell Periphery Presynapse GABA-ergic Synapse	Plasma Membrane Cell Surface Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Phosphatidylserine Binding Protein Binding Calmodulin Binding Lysophosphatidic Acid Binding Phosphatidylinositol Phosphate Binding	Protein Binding Fibrinogen Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity
	Biological Process	Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Nervous System Development Axon Guidance Response To Wounding Response To Auditory Stimulus Axon Choice Point Recognition Cell Differentiation Axon Regeneration Regulation Of Growth Tissue Regeneration Cell Fate Commitment Astrocyte Differentiation Regulation Of Filopodium Assembly Radial Glial Cell Differentiation Regulation Of Postsynaptic Specialization Assembly	Angiogenesis Positive Regulation Of Immune System Process Apoptotic Process Inflammatory Response Cell Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Cell Migration Positive Regulation Of Cell-cell Adhesion Regulation Of Type II Interferon Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Negative Regulation Of Phagocytosis Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Type II Interferon Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 Cell-cell Adhesion ATP Export Positive Regulation Of Monocyte Extravasation
Pathways		L1CAM interactions	Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) Breast size ( 22747683) Metabolite levels ( 23823483) Proliferative diabetic retinopathy ( 31482010) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Seasonality and depression ( 30217971) Urate levels in obese individuals ( 25811787)	Bipolar disorder ( 31043756 33263727 34002096) Body mass index ( 25673413) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889)
Interacting Genes		8 interacting genes: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1	17 interacting genes: BNIP3 EPB42 FAS GNAI1 ITGAV MTIF3 MUC1 P2RY2 PTK2 PVR RHAG SIRPA SRC SYNE4 THBS1 TMEM167B UBQLN1
Entrez ID		2596	961
HPRD ID		01198	03017
Ensembl ID		ENSG00000172020	ENSG00000196776
Uniprot IDs		P17677 Q5U058	A0A0A1TSG4 Q08722
PDB IDs			2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU 7MYZ 7WN8 7XJF 7YGG 8RP8
Enriched GO Terms of Interacting Partners?		Protein Kinase C Signaling Phospholipase C/protein Kinase C Signal Transduction Spectrin Diacylglycerol-dependent Serine/threonine Kinase Activity Calyx Of Held Cell Death Apoptotic Process Programmed Cell Death Presynaptic Cytosol Regulation Of Biological Quality Calcium Channel Regulator Activity Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Actin Filament Organization Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Actin Filament Polymerization Descending Aorta Development Ascending Aorta Development Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Regulation Of Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Type II Interferon Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cellular Response To Interleukin-12 Protein Serine Kinase Activity Pre-mRNA Intronic Pyrimidine-rich Binding Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Histone H3T6 Kinase Activity Positive Regulation Of Sphingomyelin Catabolic Process Regulation Of Supramolecular Fiber Organization Negative Regulation Of Transport Response To Type II Interferon Cellular Response To Cytokine Stimulus Protein Kinase CK2 Complex Protein Serine/threonine Kinase Activity Symbiont-mediated Disruption Of Host Cell PML Body Peptidyl-lysine Oxidation Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Positive Regulation Of Endodeoxyribonuclease Activity Termination Of Signal Transduction Intracellular Signal Transduction Negative Regulation Of Transmembrane Transport Protein Binding Involved In Heterotypic Cell-cell Adhesion	Response To Mechanical Stimulus Regulation Of Apoptotic Signaling Pathway Cellular Response To Stress Signaling Receptor Activity Ankyrin-1 Complex Integrin Binding Signal Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Catabolic Process Cellular Response To Hydrogen Peroxide Positive Regulation Of Phosphate Metabolic Process Regulation Of Focal Adhesion Assembly Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Cell-substrate Junction Organization Regulation Of Proteolysis Negative Regulation Of Programmed Cell Death Positive Regulation Of Fibroblast Migration Positive Regulation Of Metabolic Process Response To Hyperoxia Response To Hydrogen Peroxide Filopodium Membrane Negative Regulation Of Transport Transforming Growth Factor Beta Binding Fibroblast Growth Factor Binding Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Integrin-mediated Signaling Pathway Positive Regulation Of Phosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of Anoikis Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Glycolytic Process Cellular Response To Reactive Oxygen Species Cell Motility Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Chemical Stress Multicellular Organismal-level Iron Ion Homeostasis Symbiont Entry Into Host Cell Protein Autophosphorylation Positive Regulation Of Macrophage Migration Regulation Of Anoikis Autophagy Fibronectin Binding Regulation Of Cell Adhesion Extracellular Matrix Binding Regulation Of Cell-matrix Adhesion
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