SYF2 and CCNDBP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SYF2	CCNDBP1
Description		SYF2 pre-mRNA splicing factor	cyclin D1 binding protein 1
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Mitotic G2 DNA Damage Checkpoint Signaling Gastrulation Positive Regulation Of Cell Population Proliferation RNA Splicing Embryonic Organ Development
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Glycated hemoglobin levels ( 28898252 34059833) Lead levels ( 26025379) Male-pattern baldness ( 27182965 29146897) Mean corpuscular volume ( 27863252) Plateletcrit ( 27863252) Urate levels in obese individuals ( 25811787)
Interacting Genes		5 interacting genes: APP ARMC7 CCNDBP1 MCM3 MLH1	114 interacting genes: ADGRA2 AMPD2 AQP1 ARHGAP22 ATP4B C22orf23 CCDC146 CCDC187 CCND1 CDK18 CDKN2A CFAP65 CNNM3 CUL5 DMRT3 DOCK2 FAM110A FAM161A FAM74A4 FH FZD10 GAS2L2 GLIDR GRAP2 GSTK1 HBZ HDAC4 HMGB1 HSPB1 HYCC1 ILF2 IMP3 IRGC LIN37 LNX1 MAP2K2 MOS MRPL15 MRPS9 MTDH NAIF1 NANOS2 NEURL3 NOL7 NSMF NUDCD3 PAXIP1 PEX39 PIAS2 PIMREG PLEKHA7 PMP2 POLDIP3 POLL PRPF31 PSMB10 PTF1A RARA RARB RBP5 RPL28 RPL39L RPL7L1 RPS28 SASH1 SHFL SIRT6 SLC16A13 SPG7 STK25 SYF2 TCEAL1 TEAD4 TFPT THAP10 THAP7 TMEM120B TRAPPC5 TTC23 TYMSOS WNT11 ZBTB24 ZGPAT ZNF124 ZNF136 ZNF155 ZNF169 ZNF20 ZNF223 ZNF230 ZNF334 ZNF394 ZNF417 ZNF439 ZNF440 ZNF480 ZNF490 ZNF552 ZNF555 ZNF557 ZNF564 ZNF578 ZNF581 ZNF627 ZNF670 ZNF696 ZNF697 ZNF707 ZNF785 ZNF786 ZNF835 ZNF837 ZNRF2P1 ZSCAN26
Entrez ID		25949	23582
HPRD ID		07386	06156
Ensembl ID		ENSG00000117614	ENSG00000166946
Uniprot IDs		O95926	B4DHB5 O95273
PDB IDs		5MQF 5XJC 5YZG 6ICZ 6ID0 6ID1 6QDV 7A5P 7W59 7W5A 7W5B 8C6J 8I0U 8I0V 8I0W 8RO2 9FMD	3AY5
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Mitotic DNA Replication Initiation Single-stranded DNA Binding Alpha DNA Polymerase:primase Complex Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Chiasma Late Recombination Nodule Mismatch Repair Complex Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Mitotic Recombination Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Double-strand Break Repair Positive Regulation Of Isotype Switching To IgA Isotypes DNA Recombination	Zinc Ion Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Binding Regulation Of Macromolecule Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Heterocyclic Compound Binding Regulation Of Metabolic Process SUMO Transferase Activity
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