CCNDBP1 and RPL28

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		CCNDBP1	RPL28
Description		cyclin D1 binding protein 1	ribosomal protein L28
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body	Cytoplasm Cytosol Ribosome Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Dendrite Cytoplasmic Ribonucleoprotein Granule Cell Body Synapse Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process		Cytoplasmic Translation Translation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS			Retinitis pigmentosa ( 33514863)
Interacting Genes		114 interacting genes: ADGRA2 AMPD2 AQP1 ARHGAP22 ATP4B C22orf23 CCDC146 CCDC187 CCND1 CDK18 CDKN2A CFAP65 CNNM3 CUL5 DMRT3 DOCK2 FAM110A FAM161A FAM74A4 FH FZD10 GAS2L2 GLIDR GRAP2 GSTK1 HBZ HDAC4 HMGB1 HSPB1 HYCC1 ILF2 IMP3 IRGC LIN37 LNX1 MAP2K2 MOS MRPL15 MRPS9 MTDH NAIF1 NANOS2 NEURL3 NOL7 NSMF NUDCD3 PAXIP1 PEX39 PIAS2 PIMREG PLEKHA7 PMP2 POLDIP3 POLL PRPF31 PSMB10 PTF1A RARA RARB RBP5 RPL28 RPL39L RPL7L1 RPS28 SASH1 SHFL SIRT6 SLC16A13 SPG7 STK25 SYF2 TCEAL1 TEAD4 TFPT THAP10 THAP7 TMEM120B TRAPPC5 TTC23 TYMSOS WNT11 ZBTB24 ZGPAT ZNF124 ZNF136 ZNF155 ZNF169 ZNF20 ZNF223 ZNF230 ZNF334 ZNF394 ZNF417 ZNF439 ZNF440 ZNF480 ZNF490 ZNF552 ZNF555 ZNF557 ZNF564 ZNF578 ZNF581 ZNF627 ZNF670 ZNF696 ZNF697 ZNF707 ZNF785 ZNF786 ZNF835 ZNF837 ZNRF2P1 ZSCAN26	9 interacting genes: CCNDBP1 FNDC3B FOXP1 MAP2K5 PTEN SGO1 SMAD4 STAU1 TMEM230
Entrez ID		23582	6158
HPRD ID		06156	04702
Ensembl ID		ENSG00000166946	ENSG00000108107
Uniprot IDs		B4DHB5 O95273	H0YKD8 P46779
PDB IDs		3AY5	4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7QVP 7XNX 7XNY 8A3D 8FKQ 8FKS 8FKU 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9FPZ 9FQ0 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Binding Regulation Of Macromolecule Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Heterocyclic Compound Binding Regulation Of Metabolic Process SUMO Transferase Activity	Endothelial Cell Activation Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Growth Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Growth Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Organ Growth Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Population Proliferation Negative Regulation Of Intracellular Signal Transduction Gonad Morphogenesis Negative Regulation Of Cardiac Myofibril Assembly Nephrogenic Mesenchyme Morphogenesis Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cell Growth Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis ERK5 Cascade Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Regulation Of Organ Growth Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Axo-dendritic Transport Positive Regulation Of Interleukin-21 Production Negative Regulation Of Developmental Growth Regulation Of Chemokine Production Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Metanephric Mesenchyme Morphogenesis Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Mitotic Sister Chromatid Cohesion, Centromeric Osteoblast Differentiation Positive Regulation Of Luteinizing Hormone Secretion Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation By Virus Of Viral Protein Levels In Host Cell Regulation Of System Process Sulfate Binding Endocardial Cell Differentiation Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Smooth Muscle Cell Proliferation
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