ALS2CL and SAXO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ALS2CL	SAXO4
Description		ALS2 C-terminal like	stabilizer of axonemal microtubules 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Vesicle	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Phosphatase Binding
	Biological Process	Endosomal Transport	Flagellated Sperm Motility
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: EEF1AKMT3 RAB22A RAB31 RAB5A RAB5C RSPH14 SAXO4	73 interacting genes: AKAP8L ALS2CL APP ATN1 ATPAF2 B9D2 BAG4 BCAS2 C10orf55 CATSPER1 CCDC57 CFTR COG6 COX5B CSTF2 CTDSP1 CYSRT1 DTX2 FAM168B FHL2 FHL3 FHL5 FKBP6 FRS3 GOLGA2 HGS HNRNPH1 HOMER3 HOXA1 HSF2BP INCA1 KCTD9 KPRP KRT31 KRTAP13-2 KRTAP19-5 KRTAP19-6 KRTAP3-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LMO2 LMO4 METTL27 MYO15B OIP5 OTUD7B PFDN5 PLA2G10 PLEKHG4 PLEKHN1 PPP1CA PPP1CC PRDM14 PRKAA2 QARS1 RBM11 RFX6 RIMBP3C SLAIN1 TEKT4 TFG TGM7 TRAF1 TRAF2 TRIB3 TSC1 UNKL VMAC WWOX ZMYND12
Entrez ID		259173	220004
HPRD ID		10643	16933
Ensembl ID		ENSG00000178038	ENSG00000162148
Uniprot IDs		Q60I27	G3F4G3 Q7Z5V6
PDB IDs
Enriched GO Terms of Interacting Partners?		GDP Binding Early Endosome Endomembrane System GTPase Activity Phagocytic Vesicle Phagocytic Vesicle Membrane Plasma Membrane To Endosome Transport GTP Binding Endocytosis Regulation Of Vesicle Size Intracellular Protein Transport Import Into Cell Early Endosome Membrane Endosome Receptor Internalization Endocytic Vesicle G Protein Activity Protein Transport Endosome Organization Vesicle-mediated Transport Intracellular Transport Melanosome Ruffle Cell Projection Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization To Early Endosome Early Phagosome Membrane Cytoplasmic Side Of Early Endosome Membrane Cellular Localization Late Endosome Establishment Of Localization In Cell Receptor-mediated Endocytosis Nucleotide Binding Amyloid-beta Clearance By Transcytosis Intracellular Protein Localization Motile Cilium Cytoplasmic Vesicle Regulation Of Cellular Component Size Regulation Of Endosome Size Endosomal Transport Phagosome Maturation Early Phagosome Radial Spoke Actin Cytoskeleton Endosome Membrane Protein Localization To Endosome Positive Regulation Of Phagocytosis, Engulfment Synaptic Vesicle Recycling Somatodendritic Compartment	Intermediate Filament Protein Binding
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