H2AP and SEPTIN10

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		H2AP	SEPTIN10
Description		H2A.P histone	septin 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus	Cytoplasm Cytoskeleton Cilium Septin Ring Microtubule Cytoskeleton Septin Complex Motile Cilium Cell Division Site Cell Projection
	Molecular Function	Protein Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Heterochromatin Formation	Intracellular Protein Localization Cell Division Cytoskeleton-dependent Cytokinesis
Pathways
Drugs
Diseases
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		9 interacting genes: ATXN1 CENPH CEP44 HTT MAGEB4 MYOG NTAQ1 SEPTIN10 ZDHHC17	3 interacting genes: H2AP LSM8 YTHDC1
Entrez ID		25763	151011
HPRD ID		19386	15325
Ensembl ID		ENSG00000187516	ENSG00000186522
Uniprot IDs		O75409	B5ME97 B7Z277 B7Z371 E7EW69 Q59H84 Q9H9P7 Q9P0V9
PDB IDs
Enriched GO Terms of Interacting Partners?			Heterochromatin Formation Negative Regulation Of Gene Expression, Epigenetic MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Primary Follicle Stage Mammalian Oogenesis Stage Epigenetic Regulation Of Gene Expression MRNA Binding MRNA Alternative Polyadenylation Lsm2-8 Complex RNA Splicing U6 SnRNP MRNA Processing N6-methyladenosine-containing RNA Reader Activity U6 SnRNA Binding Precatalytic Spliceosome MRNA Metabolic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Chromatin Remodeling MRNA 3'-end Processing MRNA Splice Site Recognition Chromatin Organization U4/U6 X U5 Tri-snRNP Complex RNA Processing U2-type Precatalytic Spliceosome Negative Regulation Of Gene Expression MRNA Export From Nucleus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Export From Nucleus RNA 3'-end Processing
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