YTHDF3 and ANKHD1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		YTHDF3	ANKHD1
Description		YTH N6-methyladenosine RNA binding protein F3	ankyrin repeat and KH domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cytoplasm Cytosol Cytoplasmic Stress Granule	Nucleus Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation Negative Regulation Of Type I Interferon-mediated Signaling Pathway MRNA Destabilization Organelle Assembly Regulation Of Trophoblast Cell Migration	Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Chronotype ( 30696823) HDL cholesterol levels ( 32203549) Myocardial infarction ( 26708285) Schizophrenia ( 33169155) Smoking behaviour (cigarettes smoked per day) ( 30679032) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum immune biomarker levels ( 32066700)
Interacting Genes		17 interacting genes: ALG13 ANKHD1 CPSF7 CTTN DMRTB1 EXOSC5 FAF1 LARP4 NMD3 PRRC2B QKI RBFOX2 RBM22 RPS21 SF1 SNRPA ZDHHC17	33 interacting genes: ATXN1 ATXN1L BAG4 BCAS2 DMRTB1 EIF3E EIF4A3 EIF4ENIF1 EXOSC8 FHL3 GOLGA2 KRTAP15-1 KRTAP19-5 LENG8 LUC7L2 NFKBIE NOD2 POLR2M PRR20A PRR20B PRR20C PRR20D PRR20E PRRC2B QKI RBFOX2 RBPMS RNF10 TXNL4A UBC YTHDF3 ZNF34 ZNF346
Entrez ID		253943	54882
HPRD ID		08106	16489
Ensembl ID		ENSG00000185728	ENSG00000131503
Uniprot IDs		A0A024R7W5 A0A087WY31 B4DPX9 Q7Z739 Q8NA80	Q8IWZ3
PDB IDs		6ZOT 8BS5 8BS6
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing MRNA Metabolic Process MRNA Processing RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome MRNA Binding Cytosolic Small Ribosomal Subunit Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Nucleic Acid Metabolic Process Spliceosomal Complex Gamma-glutamyl-peptidase Activity Regulation Of RNA Splicing Internal N(7)-methylguanine-containing RNA Reader Activity Perforant Pathway To Dendrate Granule Cell Synapse Methionine Adenosyltransferase Regulator Activity N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Macromolecule Metabolic Process	RNA Binding MRNA Binding Regulation Of MRNA Metabolic Process POZ Domain Binding Membraneless Organelle Assembly RNA Metabolic Process MRNA Metabolic Process RNA Processing Negative Regulation Of Translation RNA Splicing Positive Regulation Of Myelination MRNA Splicing, Via Spliceosome Nucleus Regulation Of Translation Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Nuclear Export Regulation Of Gliogenesis Positive Regulation Of MRNA Catabolic Process Stress Granule Assembly RNA Splicing, Via Transesterification Reactions Regulation Of Nervous System Process Negative Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule MRNA Processing Internal N(7)-methylguanine-containing RNA Reader Activity Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Modification Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion P-body Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Maintenance Of ER Location
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