WDR27 and ASNS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		WDR27	ASNS
Gene Name		WD repeat domain 27	asparagine synthetase (glutamine-hydrolyzing)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Cytosol
	Molecular Function		Asparagine Synthase (glutamine-hydrolyzing) Activity ATP Binding Protein Homodimerization Activity Cofactor Binding
	Biological Process		Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Endoplasmic Reticulum Unfolded Protein Response Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus Cellular Nitrogen Compound Metabolic Process Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process
Pathways			Amino acid synthesis and interconversion (transamination) ATF4 activates genes PERK regulates gene expression Unfolded Protein Response (UPR) Metabolism of amino acids and derivatives
Drugs			L-Aspartic Acid L-Glutamic Acid Adenosine triphosphate L-Asparagine
Diseases
GWAS		Type 1 diabetes ( 21980299)
Protein-Protein Interactions		1 interactors: ASNS	4 interactors: ATXN1 STRN4 TRIM69 WDR27
Entrez ID		253769	440
HPRD ID		11352	00153
Ensembl ID		ENSG00000184465	ENSG00000070669
Uniprot IDs		A2RRH5	P08243
PDB IDs
Enriched GO Terms of Interacting Partners?		L-asparagine Biosynthetic Process Asparagine Biosynthetic Process Response To Methotrexate Asparagine Metabolic Process Response To Follicle-stimulating Hormone Cellular Response To Glucose Starvation Glutamine Metabolic Process Response To Gonadotropin Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Response To Amino Acid Cellular Response To Topologically Incorrect Protein Positive Regulation Of Mitotic Cell Cycle Response To Unfolded Protein Cellular Amino Acid Biosynthetic Process Cellular Response To Starvation Liver Development Response To Endoplasmic Reticulum Stress Response To Toxic Substance Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Response To Mechanical Stimulus Cellular Amide Metabolic Process Positive Regulation Of Cell Cycle Alpha-amino Acid Metabolic Process Response To Light Stimulus
Tagcloud ?			accordingly alters asparagine atf4 captures connection delivers extracellularly gas hemolysin inflict internalized irreversible multiplication nutrients obviating pathogens poorly senses slo sls streptococcus streptolysin synthetase toxins trigger unfolded upr
Tagcloud (Difference) ?			accordingly alters asparagine atf4 captures connection delivers extracellularly gas hemolysin inflict internalized irreversible multiplication nutrients obviating pathogens poorly senses slo sls streptococcus streptolysin synthetase toxins trigger unfolded upr
Tagcloud (Intersection) ?