FAM21C and FKBP15

Number of citations of the paper that reports this interaction (PMID 22070227)
23

Data Source:
BioGRID (two hybrid)

		FAM21C	FKBP15
Gene Name		family with sequence similarity 21, member C	FK506 binding protein 15, 133kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Early Endosome Membrane WASH Complex	Early Endosome Actin Filament Membrane Axon Growth Cone
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Actin Binding Protein Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Plasma Membrane Negative Regulation Of Barbed-end Actin Filament Capping	Protein Folding Endocytosis Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		4 interactors: ATXN1 FKBP15 KIAA0196 VPS35	1 interactors: FAM21C
Entrez ID		253725	23307
HPRD ID		11094	19414
Ensembl ID		ENSG00000172661	ENSG00000119321
Uniprot IDs		A8K5W5 B3KMC4 Q9Y4E1	Q5T1M5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Late Endosome To Lysosome Transport Endosomal Transport Intracellular Transport Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Retrograde Transport, Endosome To Plasma Membrane Transport Transcytosis Establishment Of Localization In Cell Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Localization	Negative Regulation Of Barbed-end Actin Filament Capping Regulation Of Barbed-end Actin Filament Capping Retrograde Transport, Endosome To Plasma Membrane Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Golgi Regulation Of Cell-substrate Adhesion Endosomal Transport
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