FKBP15 and FAM21C

Number of citations of the paper that reports this interaction (PMID 22070227)
23

Data Source:
BioGRID (two hybrid)

		FKBP15	FAM21C
Gene Name		FK506 binding protein 15, 133kDa	family with sequence similarity 21, member C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Actin Filament Membrane Axon Growth Cone	Endosome Early Endosome Plasma Membrane Early Endosome Membrane WASH Complex
	Molecular Function	Actin Binding Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Protein Folding Endocytosis Negative Regulation Of Phosphatase Activity	Retrograde Transport, Endosome To Golgi Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Plasma Membrane Negative Regulation Of Barbed-end Actin Filament Capping
Pathways
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		1 interactors: FAM21C	4 interactors: ATXN1 FKBP15 KIAA0196 VPS35
Entrez ID		23307	253725
HPRD ID		19414	11094
Ensembl ID		ENSG00000119321	ENSG00000172661
Uniprot IDs		Q5T1M5	A8K5W5 B3KMC4 Q9Y4E1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Barbed-end Actin Filament Capping Regulation Of Barbed-end Actin Filament Capping Retrograde Transport, Endosome To Plasma Membrane Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Golgi Regulation Of Cell-substrate Adhesion Endosomal Transport	Negative Regulation Of Late Endosome To Lysosome Transport Endosomal Transport Intracellular Transport Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Retrograde Transport, Endosome To Plasma Membrane Transport Transcytosis Establishment Of Localization In Cell Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Localization
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