RNASEH1 and TMEM11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNASEH1	TMEM11
Description		ribonuclease H1	transmembrane protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane
	Molecular Function	Magnesium Ion Binding Nucleic Acid Binding RNA Binding Nuclease Activity Endonuclease Activity RNA-DNA Hybrid Ribonuclease Activity RNA Nuclease Activity Protein Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	RNA Catabolic Process DNA Replication, Removal Of RNA Primer	Mitochondrion Organization Inner Mitochondrial Membrane Organization
Pathways		Strand-asynchronous mitochondrial DNA replication	Cristae formation
Drugs
Diseases
GWAS			Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: ASPH CRYAA EMD FAM3C NCS1 NRM TM9SF1 TMEM11 TRIM63	56 interacting genes: AQP6 ARL13B BDKRB2 BIK BNIP3 BNIP3L CCDC70 CCR4 CD79A CLDN7 CLN8 CREB3L1 CYB561 CYB5D2 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FATE1 FFAR2 GJB4 GORAB GPX8 KASH5 LEPROTL1 LMNA MRM1 MSMO1 MTIF3 MUC1 NDUFS3 OTX2 PDZK1IP1 PEX12 RETREG3 RIC3 RNASEH1 SCMH1 SGCB SLC10A6 SLC30A8 SUSD3 SUV39H1 TEX29 TMEM106C TMEM14B TMEM205 TMEM237 TMEM88 TMIE TMPRSS2 TNFSF14 YIPF6
Entrez ID		246243	8834
HPRD ID		04989	12680
Ensembl ID		ENSG00000171865	ENSG00000178307
Uniprot IDs		B3KUD4 E5KN15 O60930	P17152
PDB IDs		2QK9 2QKB 2QKK 3BSU 6VRD 8SWB 8SWC
Enriched GO Terms of Interacting Partners?		Cortical Endoplasmic Reticulum Muscle System Process Muscle Contraction Regulation Of Intracellular Transport Nuclear Inner Membrane TMEM240-body Peptidyl-aspartic Acid 3-dioxygenase Activity Positive Regulation Of Intracellular Protein Transport Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation	Membrane Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity
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