ALOX15B

Gene Name		arachidonate 15-lipoxygenase, type B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Extrinsic Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Iron Ion Binding Calcium Ion Binding Lipid Binding Linoleate 13S-lipoxygenase Activity Arachidonate 8(S)-lipoxygenase Activity Arachidonate 15-lipoxygenase Activity
	Biological Process	Lipid Metabolic Process Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Arachidonic Acid Metabolic Process Lipoxygenase Pathway Negative Regulation Of Cell Migration Prostate Gland Development Regulation Of Epithelial Cell Differentiation Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Linoleic Acid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Keratinocyte Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Growth Hepoxilin Biosynthetic Process Oxidation-reduction Process Positive Regulation Of Chemokine Secretion
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Synthesis of 15-eicosatetraenoic acid derivatives
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: PPARG RXRA
Entrez ID		247
HPRD ID		04739
Ensembl ID		ENSG00000179593
Uniprot IDs		I3L1D5 O15296
PDB IDs
Enriched GO Terms of Interacting Partners?		Peroxisome Proliferator Activated Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Retinoic Acid Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Placenta Development Intracellular Receptor Signaling Pathway Response To Metformin Response To Diuretic Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation DNA-templated Transcription, Initiation Cellular Response To Vitamin E Positive Regulation Of Translational Initiation By Iron Regulation Of Cholesterol Transporter Activity Cellular Response To Organic Cyclic Compound Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Response To Lipid Negative Regulation Of Collagen Biosynthetic Process Response To Steroid Hormone Reproductive Structure Development Negative Regulation Of Receptor Biosynthetic Process Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Reproductive System Development Heart Development Cellular Response To Hyperoxia Receptor Biosynthetic Process Negative Regulation Of Multicellular Organismal Metabolic Process Epithelial Cell Differentiation Negative Regulation Of Sequestering Of Triglyceride Negative Regulation Of Cholesterol Storage Negative Regulation Of Telomerase Activity Cellular Response To Hormone Stimulus Regulation Of Branching Involved In Prostate Gland Morphogenesis Cellular Response To Prostaglandin E Stimulus Developmental Process Involved In Reproduction Negative Regulation Of Acute Inflammatory Response Regulation Of Telomerase Activity Response To Low-density Lipoprotein Particle Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Phagocytosis, Engulfment Positive Regulation Of Translational Initiation Cellular Response To Lithium Ion Positive Regulation Of Fatty Acid Oxidation White Fat Cell Differentiation Response To Lipid Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Receptor Biosynthetic Process Cellular Response To Prostaglandin Stimulus
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