PPT2

Description		palmitoyl-protein thioesterase 2
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GO Annotations	Cellular Component	Extracellular Region Lysosome Lysosomal Lumen Extracellular Exosome
	Molecular Function	Hydrolase Activity Thiolester Hydrolase Activity Fatty Acyl-CoA Hydrolase Activity Palmitoyl Hydrolase Activity
	Biological Process	Fatty-acyl-CoA Biosynthetic Process Macromolecule Depalmitoylation
Pathways		Fatty acyl-CoA biosynthesis
Drugs
Diseases
GWAS		Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) Autism spectrum disorder or schizophrenia ( 28540026) Birth weight ( 31043758) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Offspring birth weight ( 31043758) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Prostate cancer ( 23535732) Pulmonary function ( 20010835) Ulcerative colitis ( 28067908)
Interacting Genes		1 interacting genes: BCL2L13
Entrez ID		9374
HPRD ID		04486
Ensembl ID		ENSG00000221988
Uniprot IDs		A0A1U9X8D2 Q9UMR5
PDB IDs		1PJA
Enriched GO Terms of Interacting Partners?		Mitophagy Glycolytic Process Through Glucose-6-phosphate ADP Catabolic Process Oxidative Phosphorylation ADP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Glycolytic Process Glycolytic Process Through Fructose-6-phosphate Glucose Catabolic Process Canonical Glycolysis Ribonucleoside Diphosphate Catabolic Process Pyruvate Metabolic Process Purine Ribonucleotide Catabolic Process Ribonucleoside Diphosphate Metabolic Process Autophagy Of Mitochondrion Purine Nucleotide Catabolic Process Nucleoside Diphosphate Metabolic Process Aerobic Respiration Cellular Respiration Nucleotide Catabolic Process Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Glucose Metabolic Process Nucleoside Phosphate Catabolic Process Fat Cell Differentiation Mitochondrial Membrane Monosaccharide Metabolic Process ATP Metabolic Process Carbohydrate Derivative Catabolic Process Organophosphate Catabolic Process Energy Derivation By Oxidation Of Organic Compounds Macroautophagy Hexose Metabolic Process Mitochondrion Organization Purine Ribonucleotide Metabolic Process Autophagy Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Generation Of Precursor Metabolites And Energy Nucleobase-containing Compound Catabolic Process Purine Nucleotide Metabolic Process Carbohydrate Metabolic Process Nucleotide Metabolic Process Monocarboxylic Acid Metabolic Process Purine-containing Compound Metabolic Process Nucleoside Phosphate Metabolic Process
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