WBP2 and EEF1B2

Number of citations of the paper that reports this interaction (PubMedID 27578003)
0

Data Source:
BioGRID (pull down)

		WBP2	EEF1B2
Description		WW domain binding protein 2	eukaryotic translation elongation factor 1 beta 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Estrogen Receptor Binding Chromatin DNA Binding	Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Establishment Of Protein Localization To Chromatin Cellular Response To Estrogen Stimulus	Translation Translational Elongation Response To Ethanol
Pathways			Eukaryotic Translation Elongation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Platelet count ( 32888494) Red blood cell count ( 32888494) White matter hyperintensities ( 32358547)	Body mass index ( 26426971)
Interacting Genes		54 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 BAG3 CCT7 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HUWE1 ITCH KRT18 KRT8 KRT9 LGALS8 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 RUNX1 SDHA SEPTIN3 SMAD5 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE2E3 UBE3A UBQLN1 UIMC1 WWC3 WWP1 WWP2 WWTR1 YAP1	15 interacting genes: AARS1 APP CEBPA CSNK2A1 CSNK2A2 DRD3 EEF1G HARS1 SPRYD4 TIMP1 TPT1 ULK2 USP7 VHL WBP2
Entrez ID		23558	1933
HPRD ID		06097	02804
Ensembl ID		ENSG00000132471	ENSG00000114942
Uniprot IDs		A6NG10 Q969T9	P24534
PDB IDs			1B64 5DQS
Enriched GO Terms of Interacting Partners?		COPI Vesicle Coat COPI-coated Vesicle Membrane Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Cytosol Protein Ubiquitination Protein Modification By Small Protein Conjugation COPI-coated Vesicle Intra-Golgi Vesicle-mediated Transport Macromolecule Catabolic Process Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein Polyubiquitination Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Transport Vesicle Protein Monoubiquitination Nucleoplasm Protein K48-linked Ubiquitination Structural Molecule Activity Membrane Coat Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Proteolysis Cytoplasm Potassium Channel Inhibitor Activity Protein K63-linked Ubiquitination Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Nephron Tubule Epithelial Cell Differentiation Extracellular Exosome Catabolic Process Protein Tag Activity Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Ubiquitin Protein Ligase Activity Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Proteasomal Protein Catabolic Process Nuclear Receptor-mediated Signaling Pathway Ubiquitin Binding Protein Catabolic Process Golgi Vesicle Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Branched Polyubiquitination Histone Ubiquitin Ligase Activity Intracellular Protein Transport Negative Regulation Of Potassium Ion Transmembrane Transport Vesicle-mediated Transport Cytoplasmic Vesicle Cardiac Muscle Tissue Regeneration Intracellular Protein Localization Negative Regulation Of Cation Transmembrane Transport	Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Proteolysis Regulation Of Protein Catabolic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Signal Transduction Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Apoptotic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Autophagy Regulation Of Programmed Cell Death Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Collateral Sprouting Regulation Of Neurotransmitter Uptake Regulation Of Signal Transduction By P53 Class Mediator Protein Serine/threonine Kinase Binding Regulation Of Protein Metabolic Process Regeneration Regulation Of Membrane Protein Ectodomain Proteolysis Signal Transduction PcG Protein Complex Cellular Response To Stress Amyloid Fibril Formation Protein Metabolic Process Cytosol TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity DNA-binding Transcription Factor Binding TRNA Aminoacylation Response To Stress Macromolecule Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cytoplasmic Translational Fidelity
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