RASD2 and SUN2

		RASD2	SUN2
Description		RASD family member 2	Sad1 and UNC84 domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Nuclear Envelope Nuclear Inner Membrane Endosome Endosome Membrane Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Nucleotide Binding GTPase Activity GTP Binding G-protein Beta-subunit Binding	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	Synaptic Transmission, Dopaminergic Signal Transduction Locomotory Behavior Positive Regulation Of Protein Sumoylation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane
Pathways			Meiotic synapsis
Drugs
Diseases
GWAS		Chronotype ( 30696823) Hippocampal volume in mild cognitive impairment ( 29274321) Intelligence (MTAG) ( 29326435) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		16 interacting genes: ACVR1 BMPR1B GNB1 GNB2 GNB3 PIK3CA PIK3R1 RABAC1 RAF1 SMAD1 SMAD2 SMAD3 SMAD4 SMURF1 SMURF2 TGFBR1	6 interacting genes: HGS NRM PRPF6 RAB5B RPS20 SRSF10
Entrez ID		23551	25777
HPRD ID		15210	15611
Ensembl ID		ENSG00000100302	ENSG00000100242
Uniprot IDs		Q96D21	B0QY60 B0QY64 B4E2A6 Q9UH99
PDB IDs			3UNP 4DXR 4DXS 4DXT 4FI9 6WMD 6WME 6WMF 6WMG
Enriched GO Terms of Interacting Partners?		I-SMAD Binding SMAD Binding Enzyme-linked Receptor Protein Signaling Pathway Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Heteromeric SMAD Protein Complex Activin Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Activity, Type I SMAD Protein Signal Transduction Response To Growth Factor Regulation Of Developmental Process R-SMAD Binding BMP Signaling Pathway Intracellular Glucose Homeostasis Cell Surface Receptor Signaling Pathway Regulation Of Cell Differentiation Trophoblast Cell Migration Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway GTPase Binding Pattern Specification Process Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Extracellular Matrix Assembly Gastrulation Osteoblast Differentiation Ameboidal-type Cell Migration Tissue Development Regionalization Transmembrane Receptor Protein Serine/threonine Kinase Activity Co-SMAD Binding Cellular Response To Growth Factor Stimulus Primary MiRNA Processing Embryonic Pattern Specification Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Binding Positive Regulation Of Signal Transduction Regulation Of SMAD Protein Signal Transduction Intracellular Signaling Cassette Response To Transforming Growth Factor Beta Cell Fate Commitment Positive Regulation Of Cell Differentiation Regulation Of Cartilage Development Positive Regulation Of Multicellular Organismal Process Homomeric SMAD Protein Complex Glucose Homeostasis	Endosome Organization Spliceosomal Tri-snRNP Complex Assembly
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