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TTC33 and TCL1A
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid)
TTC33
TCL1A
Description
tetratricopeptide repeat domain 33
TCL1 family AKT coactivator A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Molecular Function
Protein Binding
Protein Binding
Protein Kinase Binding
Identical Protein Binding
Protein Serine/threonine Kinase Activator Activity
Biological Process
Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
Gastric cancer (
26098866
)
Adverse response to aromatase inhibitors (
20876420
)
Mosaic loss of chromosome Y (
27064253
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
28346444
31624269
)
Plateletcrit (
32888494
)
Refractive error (
32231278
)
Interacting Genes
6 interacting genes:
KDM1A
MITD1
PSMB1
SMYD1
TCL1A
TXLNA
37 interacting genes:
AKT1
AKT2
AKT3
ATM
CADPS
CALCOCO2
CARD9
CASP8AP2
CCDC13
CEP55
DDIT4L
FLACC1
GOLGA2
H2AC25
INCA1
LNX1
LNX2
LSM3
NFKBIA
NFKBID
NIF3L1
NTAQ1
PPP1R13B
PRTFDC1
REL
TAX1BP1
TCF4
TEPSIN
TNKS
TP53BP2
TRAF1
TRAF2
TRMT61A
TTC33
TXLNA
TXLNB
WDR47
Entrez ID
23548
8115
HPRD ID
17807
01744
Ensembl ID
ENSG00000113638
ENSG00000100721
Uniprot IDs
Q6PID6
P56279
PDB IDs
1JSG
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of PERK-mediated Unfolded Protein Response
Regulation Of PERK-mediated Unfolded Protein Response
Apoptotic Signaling Pathway
Identical Protein Binding
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
Cytoplasm
Signaling Adaptor Activity
Non-canonical NF-kappaB Signal Transduction
Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Regulation Of Canonical NF-kappaB Signal Transduction
Apoptotic Process
Toll-like Receptor 4 Signaling Pathway
Peptidyl-serine Phosphorylation
Negative Regulation Of Fatty Acid Transport
Programmed Cell Death
Regulation Of Long-chain Fatty Acid Import Into Cell
Peripheral Nervous System Myelin Maintenance
Cell Death
Cell Surface Toll-like Receptor Signaling Pathway
Negative Regulation Of Lipid Transport
Protein Binding
Regulation Of Apoptotic Process
Negative Regulation Of Response To Endoplasmic Reticulum Stress
Syntaxin Binding
Regulation Of Programmed Cell Death
Thioesterase Binding
Cell Surface Pattern Recognition Receptor Signaling Pathway
Tumor Necrosis Factor-mediated Signaling Pathway
Protein Polyubiquitination
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Telomere Capping
Myelin Maintenance
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Mammary Gland Epithelial Cell Differentiation
Glycogen Biosynthetic Process
Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Glycogen Biosynthetic Process
Insulin Receptor Signaling Pathway
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of T-helper 17 Type Immune Response
Negative Regulation Of Cell Cycle
Response To Muramyl Dipeptide
Intracellular Signal Transduction
Peptidyl-threonine Phosphorylation
Regulation Of Response To Endoplasmic Reticulum Stress
Polysaccharide Biosynthetic Process
Positive Regulation Of Telomere Maintenance Via Telomerase
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Tagcloud (Intersection)
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