POFUT1 and NAP1L2

		POFUT1	NAP1L2
Description		protein O-fucosyltransferase 1	nucleosome assembly protein 1 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Chromatin Nucleus
	Molecular Function	Transferase Activity Glycosyltransferase Activity Peptide-O-fucosyltransferase Activity	Chromatin Binding Protein Binding Histone Acetyltransferase Regulator Activity Histone Binding
	Biological Process	Angiogenesis Somitogenesis Fucose Metabolic Process Protein Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway Protein O-linked Glycosylation Via Fucose	Nucleosome Assembly Neuron Differentiation Positive Regulation Of Neuron Differentiation Regulation Of Stem Cell Division
Pathways		Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)	Bipolar disorder ( 31043756)
Interacting Genes		4 interacting genes: AKT2 DLL1 JAG1 NOTCH1	14 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 OLIG2 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110
Entrez ID		23509	4674
HPRD ID		06319	02066
Ensembl ID		ENSG00000101346	ENSG00000186462
Uniprot IDs		Q9H488	Q9ULW6
PDB IDs		5UX6 5UXH
Enriched GO Terms of Interacting Partners?		Neuron Differentiation Inhibition Of Neuroepithelial Cell Differentiation Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Left/right Axis Specification Inner Ear Auditory Receptor Cell Differentiation Hair Cell Differentiation Inner Ear Receptor Cell Differentiation Epidermal Cell Differentiation Nephron Tubule Development Renal Tubule Development Neuronal Stem Cell Population Maintenance Notch Binding Mechanoreceptor Differentiation Tube Morphogenesis Stem Cell Population Maintenance Maintenance Of Cell Number Neuroepithelial Cell Differentiation Distal Tubule Development Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Compartment Pattern Specification Positive Regulation Of Notch Signaling Pathway Loop Of Henle Development Negative Regulation Of Epithelial Cell Differentiation Epithelial Cell Differentiation Regulation Of Somitogenesis Regulation Of Neuron Differentiation Heart Looping Embryonic Heart Tube Morphogenesis Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Kidney Epithelium Development Negative Regulation Of Neuron Differentiation Epithelium Development Regulation Of Inner Ear Auditory Receptor Cell Differentiation Axis Specification Regulation Of Embryonic Development Nephron Development Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Regulation Of Notch Signaling Pathway Negative Regulation Of Epidermal Cell Differentiation Regulation Of Cell Differentiation Blood Vessel Morphogenesis Notch Signaling Pathway Pulmonary Valve Morphogenesis Epithelial Tube Morphogenesis Morphogenesis Of An Epithelium Cell Differentiation Neuroendocrine Cell Differentiation
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