SLC3A1

Description		solute carrier family 3 member 1
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GO Annotations	Cellular Component	Vacuolar Membrane Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	Carbohydrate Metabolic Process Amino Acid Transport Gene Expression Basic Amino Acid Transport Aspartate Transmembrane Transport L-cystine Transport L-glutamate Transmembrane Transport Basic Amino Acid Transmembrane Transport
Pathways		Amino acid transport across the plasma membrane Defective SLC3A1 causes cystinuria (CSNU) Defective SLC7A9 causes cystinuria (CSNU)
Drugs
Diseases		Cystinuria
GWAS		antipsychotic drug dosage in schizophrenia or schizoaffective disorder ( 26821981) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: NPTX1
Interacting Genes		1 interacting genes: SLC7A8
Entrez ID		6519
HPRD ID		00090
Ensembl ID		ENSG00000138079
Uniprot IDs		A0A0S2Z4E1 B8ZZK1 Q07837
PDB IDs		6LI9 6LID 6YUP 6YUZ
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Assembly Axonogenesis Involved In Innervation Mitochondrial Fragmentation Involved In Apoptotic Process Postsynaptic Specialization Assembly L-alanine Transport Tryptophan Transport Branched-chain Amino Acid Transport Proline Transmembrane Transport Organic Cation Transmembrane Transporter Activity Aromatic Amino Acid Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Transport L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport Thyroid Hormone Transport Glycine Transport Cellular Response To Potassium Ion L-amino Acid Transmembrane Transporter Activity Alanine Transport Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Postsynaptic Density Organization Neutral L-amino Acid Transmembrane Transporter Activity Response To Potassium Ion Synaptic Cleft Postsynaptic Specialization Organization Microvillus Membrane Amino Acid Transmembrane Transporter Activity Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Mitochondrial Transport Amino Acid Import Across Plasma Membrane Peptide Antigen Binding Neutral Amino Acid Transport Receptor Localization To Synapse L-alpha-amino Acid Transmembrane Transport Protein Localization To Synapse Cellular Response To Glucose Stimulus Protein-containing Complex Localization Apoptotic Mitochondrial Changes Basal Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels L-amino Acid Transport Cellular Response To Carbohydrate Stimulus Transport Across Blood-brain Barrier
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