TMEM208 and REEP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM208	REEP2
Description		transmembrane protein 208	receptor accessory protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuole Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Plasma Membrane Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Taste Receptor Binding
	Biological Process	Vacuolar Protein Processing Autophagy	Regulation Of Intracellular Transport Protein Transport Into Membrane Raft Sensory Perception Of Bitter Taste Sensory Perception Of Sweet Taste Endoplasmic Reticulum Tubular Network Organization
Pathways
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061)
Interacting Genes		23 interacting genes: C10orf67 CREB3L1 EBP FAM209A GPR152 GPRC5D KCNJ6 LMNA NDRG4 PGRMC2 REEP2 REEP4 RNF19B SCARA5 SCN3B SLC10A6 SLC30A8 SLC71A2 SLC7A8 SPG21 STOM TMEM31 TMX2	24 interacting genes: BNIP3 C2CD2L CMTM5 CYP4F2 CYP4F22 ITGAM MS4A1 MUL1 NAT8 ORMDL3 RABAC1 SCD SFT2D2 SLC25A46 TMBIM6 TMEM120B TMEM208 TMEM239 TMEM31 TMEM42 TMEM60 TMX2 TTPA YIF1A
Entrez ID		29100	51308
HPRD ID		13710	16655
Ensembl ID		ENSG00000168701	ENSG00000132563
Uniprot IDs		J3KRY7 Q9BTX3	A8K3D2 Q9BRK0
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Monoatomic Cation Transport Metal Ion Transport Nuclear Envelope Organization Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization	Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Vitamin E Metabolic Process Negative Regulation Of Mitochondrial Fusion Regulation Of Mitochondrial Fusion Mitochondrial Fission Membrane Organization Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Organization Iron Ion Binding
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