PHF24 and TRIM35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHF24	TRIM35
Description		PHD finger protein 24	tripartite motif containing 35
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Synaptic Vesicle Membrane Glutamatergic Synapse	Nucleus Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Gamma-aminobutyric Acid Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of DNA-templated Transcription Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Suppression Of Viral Release By Host Innate Immune Response Negative Regulation Of Mitotic Cell Cycle
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)
Interacting Genes		5 interacting genes: GNAI3 PFDN5 THBD TRIM35 ZNF552	50 interacting genes: ADIPOQ ANTXR1 BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410
Entrez ID		23349	23087
HPRD ID		19412	15553
Ensembl ID		ENSG00000122733	ENSG00000104228
Uniprot IDs		Q9UPV7	E5RGB3 Q9UPQ4
PDB IDs		1WIL 5XHT
Enriched GO Terms of Interacting Partners?		RNA Polymerase III Assembly RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly Blood Coagulation, Common Pathway	Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein Polyubiquitination Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin Protein Ligase Activity Transferase Activity Host-mediated Suppression Of Symbiont Invasion Protein Metabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Host-mediated Perturbation Of Symbiont Process Macromolecule Metabolic Process Modulation Of Process Of Another Organism Protein Binding Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process
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