MGA and MAX

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid, two hybrid)

		MGA	MAX
Gene Name		MGA, MAX dimerization protein	MYC associated factor X
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Cytoplasm MLL1 Complex	Nucleus Nucleoplasm Cytoplasm PML Body Dendrite MLL1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity	Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding Protein Complex Binding Protein Homodimerization Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Protein Complex Assembly Cellular Response To Starvation Negative Regulation Of Gene Expression Response To Insulin Response To Axon Injury Neuron Apoptotic Process Retina Development In Camera-type Eye Cellular Response To Peptide Hormone Stimulus
Pathways			G1/S Transition Cyclin E associated events during G1/S transition S Phase Cyclin A:Cdk2-associated events at S phase entry Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Anthropometric traits ( 19260139) Blood trace element (Zn levels) ( 23720494) Obesity-related traits ( 23251661) Red blood cell traits ( 23222517)
Protein-Protein Interactions		8 interactors: CBX3 E2F1 E2F3 E2F4 HIST3H3 LSM8 MAX SMAD1	43 interactors: BANP CASP5 CASP7 CLIP2 COPS5 CSNK2A1 CUX1 EP300 EPAS1 FTH1 FUS GABBR1 HIF1A MAD1L1 MAPK14 MGA MNT MSH2 MXD1 MXD3 MXD4 MXI1 MYC MYCL MYCLP1 MYCN PLEKHA5 PLEKHF2 PLIN3 RPL34 RPL35 SMAD3 SMAD4 SNIP1 SPAG9 TAF1 TCF3 TEAD1 TRRAP TUBA1A TXLNG UNC45A ZBTB17
Entrez ID		23269	4149
HPRD ID		19055	01113
Ensembl ID		ENSG00000174197	ENSG00000125952
Uniprot IDs		B9EGR5 Q8IWI9	P61244 Q8TAX8
PDB IDs			1AN2 1HLO 1NKP 1NLW 1R05
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Transcription, DNA-templated Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Proliferation Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Notch Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process G1/S Transition Of Mitotic Cell Cycle Lens Fiber Cell Apoptotic Process Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Multi-ciliated Epithelial Cell Differentiation Primary MiRNA Processing Cellular Response To Organic Substance Anoikis DNA-templated Transcription, Initiation Osteoblast Fate Commitment Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Motile Cilium Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter SMAD Protein Complex Assembly Mesodermal Cell Fate Commitment Response To Organic Substance	RNA Biosynthetic Process RNA Metabolic Process Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transforming Growth Factor Beta2 Production Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Catabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Tube Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Metabolic Process Negative Regulation Of Cell Division Multicellular Organismal Development Negative Regulation Of Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Embryo Development Positive Regulation Of Cell Development Regulation Of Cellular Process Cellular Metabolic Process
Tagcloud ?		absorbed attack c5b c9 complement connected determinant erythrocytes guinea histidine hrg lysis m1 m57 name overlapping possesses pyogenes regulon sensitized sepharose serotype serotypes sheep sic streptococcal streptococcus translates virulence	aminoiminomethyl behaves competitive dichloro dimethylquinolin displaced giving henyl int ips lf m1 muscarinic nonpeptide oxymethyl pa2 phenylcarbonyl phosphoinositosides piperazin plot pyrrolidine rbonyl saturation schild shifted slope sulphonyl umbilical unity yl
Tagcloud (Difference) ?		absorbed attack c5b c9 complement connected determinant erythrocytes guinea histidine hrg lysis m57 name overlapping possesses pyogenes regulon sensitized sepharose serotype serotypes sheep sic streptococcal streptococcus translates virulence	aminoiminomethyl behaves competitive dichloro dimethylquinolin displaced giving henyl int ips lf muscarinic nonpeptide oxymethyl pa2 phenylcarbonyl phosphoinositosides piperazin plot pyrrolidine rbonyl saturation schild shifted slope sulphonyl umbilical unity yl
Tagcloud (Intersection) ?		m1