MAX and MXD3

Number of citations of the paper that reports this interaction (PMID 8521822)
57

Data Source:
HPRD (in vitro)

		MAX	MXD3
Gene Name		MYC associated factor X	MAX dimerization protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm PML Body Dendrite MLL1 Complex	Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding Protein Complex Binding Protein Homodimerization Activity Sequence-specific DNA Binding Protein Heterodimerization Activity	DNA Binding Protein Dimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Protein Complex Assembly Cellular Response To Starvation Negative Regulation Of Gene Expression Response To Insulin Response To Axon Injury Neuron Apoptotic Process Retina Development In Camera-type Eye Cellular Response To Peptide Hormone Stimulus	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		G1/S Transition Cyclin E associated events during G1/S transition S Phase Cyclin A:Cdk2-associated events at S phase entry Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Anthropometric traits ( 19260139) Blood trace element (Zn levels) ( 23720494) Obesity-related traits ( 23251661) Red blood cell traits ( 23222517)	Activated partial thromboplastin time ( 22703881) Obesity-related traits ( 23251661)
Protein-Protein Interactions		43 interactors: BANP CASP5 CASP7 CLIP2 COPS5 CSNK2A1 CUX1 EP300 EPAS1 FTH1 FUS GABBR1 HIF1A MAD1L1 MAPK14 MGA MNT MSH2 MXD1 MXD3 MXD4 MXI1 MYC MYCL MYCLP1 MYCN PLEKHA5 PLEKHF2 PLIN3 RPL34 RPL35 SMAD3 SMAD4 SNIP1 SPAG9 TAF1 TCF3 TEAD1 TRRAP TUBA1A TXLNG UNC45A ZBTB17	6 interactors: KRTAP10-7 MAGEA11 MAX NOTCH2NL SIN3A SMC3
Entrez ID		4149	83463
HPRD ID		01113	14791
Ensembl ID		ENSG00000125952	ENSG00000213347
Uniprot IDs		P61244 Q8TAX8	B4E0J1 Q9BW11
PDB IDs		1AN2 1HLO 1NKP 1NLW 1R05
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process RNA Metabolic Process Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transforming Growth Factor Beta2 Production Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Catabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Tube Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Metabolic Process Negative Regulation Of Cell Division Multicellular Organismal Development Negative Regulation Of Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Embryo Development Positive Regulation Of Cell Development Regulation Of Cellular Process Cellular Metabolic Process	Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Positive Regulation Of Chromatin Silencing Negative Regulation Of DNA Endoreduplication Cellular Response To Stress Regulation Of DNA Endoreduplication Mitotic Sister Chromatid Cohesion Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Cell Cycle Process Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Defense Response To Virus By Host Developmental Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Histone Acetylation Regulation Of Gene Silencing Negative Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Protein Acetylation Regulation Of Transcription Regulatory Region DNA Binding Response To Wounding Sister Chromatid Cohesion Regulation Of Defense Response To Virus By Host Cellular Response To Stimulus Response To Organonitrogen Compound Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Mitotic Spindle Organization Transcription From RNA Polymerase II Promoter Negative Regulation Of DNA Binding Negative Regulation Of DNA Replication Regulation Of Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Phase Transition Cellular Response To Glucose Stimulus Neuron Apoptotic Process Chromosome Organization Cell Differentiation Response To Stress Histone Deacetylation Neuron Death DNA Metabolic Process Response To Axon Injury Protein Deacetylation Cellular Glucose Homeostasis
Tagcloud ?		aminoiminomethyl behaves competitive dichloro dimethylquinolin displaced giving henyl int ips lf m1 muscarinic nonpeptide oxymethyl pa2 phenylcarbonyl phosphoinositosides piperazin plot pyrrolidine rbonyl saturation schild shifted slope sulphonyl umbilical unity yl	apoptotic change daoy donors enriched g0 g1 g2 healthy hematopoietic highly knock leukemia line lymphoblastic marrow medulloblastoma mobilized mononuclear numbers peripheral plays populations possibly preb precursor reh resulted stem
Tagcloud (Difference) ?		aminoiminomethyl behaves competitive dichloro dimethylquinolin displaced giving henyl int ips lf m1 muscarinic nonpeptide oxymethyl pa2 phenylcarbonyl phosphoinositosides piperazin plot pyrrolidine rbonyl saturation schild shifted slope sulphonyl umbilical unity yl	apoptotic change daoy donors enriched g0 g1 g2 healthy hematopoietic highly knock leukemia line lymphoblastic marrow medulloblastoma mobilized mononuclear numbers peripheral plays populations possibly preb precursor reh resulted stem
Tagcloud (Intersection) ?